Abstract
Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®)
Introduction
Octenisept® is an antiseptic solution which is intended to be applied on the skin, mucous membranes and wounds.
Objective
To present a case study of a bullous skin lesions, which occurred in a 4-year-old girl after Octenisept® application, and to highlight various possible side effects of this preparation.
Case report
In a 4-year-old girl Octenisept® was applied preventively three times at intervals of 12 hours on an epidermal abrasion. Erythema and hydropic papules emerged 6–8 hours after application and were followed by vesicles and bullae 8 hours later. In spite of the topical treatment with glucocorticoids and an antibiotic, the lesions persisted for several weeks.
Conclusions
Taking into consideration the wide usage of Octenisept® in many fields of medicine, there is a need to conduct further research on the allergic potential and toxicity of this product.
Keywords
adverse effects, Octenisept®, bullous skin lesion reaction
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