eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
1/2022
vol. 109
 
Share:
Share:
more
 
 
abstract:
Original article

Cardiovascular risk factors in patients of lichen planus

Satish Sharma
1
,
Konchok Dorjay
1
,
Surabhi Sinha
1
,
Prafulla Sharma
1

1.
Dr. Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India
Dermatol Rev/Przegl Dermatol 2022, 109, 23-31
Online publish date: 2022/05/31
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
Lichen planus is a chronic inflammatory disorder in which a delayed type of hypersensitivity immune reaction plays a major role in the pathogenesis. The disease and mainly affects skin, mucous membranes, nails and hair follicles.

Objective
To study cardiovascular risk factors (metabolic syndrome and lipid profile) in patients of lichen planus.

Material and methods
Fifty patients of lichen planus aged 18 years or above and fifty age- and sex-matched controls without any evidence of skin disorder including lichen planus were enrolled. Atherosclerotic risk factors were evaluated as per National Cholesterol Education Project Adult Treatment Panel III (NCEP-ATPIII). Metabolic syndrome was defined as per the definition of the South Asian Modified criteria of NCEP-ATPIII11.

Results
The mean total cholesterol was 179.2 ±29.74 and 164.74 ±22.18 mg/dl in lichen planus patients and controls, respectively, and the difference was found to be significant (p = 0.006). A significant difference between patients and controls was also found for low-density lipoprotein (p = 0.001). Although all atherosclerotic factors were elevated in patients compared to controls, the difference was statistically significant only for body mass index (p = 0.003989).

Conclusions
The present study found a higher prevalence of dyslipidemia with a significant association between lichen planus and higher total cholesterol and low-density lipoprotein lipids. Body mass index, blood pressure and blood glucose were also higher in patients with lichen planus.

keywords:

lichen planus, metabolic syndrome, dyslipidemia

Quick links
© 2022 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.