eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
2/2008
vol. 33
 
Share:
Send email
Share:
abstract:

Clinical immunology
Analysis of genetic polymorphisms of the interleukin-1 gene in the implantoprosthetic group of patients – preliminary studies

Marta Jaworska-Zaremba
,
Elżbieta Mierzwińska-Nastalska
,
Łukasz Łomżyński
,
Katarzyna Popko
,
Maria Wąsik

(Centr Eur J Immunol 2008; 33 (2): 74-77)
Online publish date: 2008/05/05
View full text Get citation
 
One of the most frequent causes of failures in the implantoprosthetic treatment, often leading to the loss of implant is bone atrophy around the implant. There are some reports of an inhibitory influence of IL-1 on bone formation process and density of the bone tissue.
The aim of the study was the analysis of genetic polymorphisms of the interleukin-1 gene in patients treated or qualified for the prosthetic treatment with endosseous implants use.
Material for the study was full blood sampled for anticoagulant (EDTA), obtained from 20 patients with full of partial loss of teeth, aged 21-60, who were treated implantologically or were waiting for the treatment with Branemark implants use (Nobel Biocare AB).
Analysis of performed tests showed that in case of patients with IL-1B-511 2/2 genotype marginal bone loss >0.5 mm occurs more frequently than in case of patients with IL-1B-511 1/2 and IL-1B-511 1/1 genotypes.
keywords:

marginal bone loss, gene, polymorphism, interleukin-1, dental implant

Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.