Clinical immunology<br> The effect of cigarette smoking on IgE levels and circulating lymphocytes in cord blood

Wanda Karwowska; Jadwiga Rachtan; Ewa Wieczorek

eISSN: 1644-4124
ISSN: 1426-3912

Central European Journal of Immunology

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4/2008
vol. 33

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abstract:

Clinical immunology
The effect of cigarette smoking on IgE levels and circulating lymphocytes in cord blood

Wanda Karwowska

,

Jadwiga Rachtan

,

Ewa Wieczorek

Centr Eur J Immunol 2008; 33 (4): 228-231

Online publish date: 2008/12/24

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Mechanisms of smoking-induced morbidity and mortality include a lower birth weight, preterm delivery, and abruptio placentae. This study showed the effects of nicotine on cellular proliferation and elevated level of the immunoglobulin E in newborns. This analysis of cord blood markers was part of a larger study of maternal inflammatory response to smoking during pregnancy. Newborns of smokers and exposure to smoking mothers elevated level of the IgE. The proportion of CD4+ T cells in smokers compared to non-smokers mothers (p=0.02). There was no significant difference in the percent of CD8+ cells between smokers and all other subjects during pregnancy at the time-points analysed.

keywords:

Clinical immunology The effect of cigarette smoking on IgE levels and circulating lymphocytes in cord blood

Wanda Karwowska , Jadwiga Rachtan , Ewa Wieczorek

pregnant women, cord blood, newborns, immunoglobulin E, lymphocytes T

Clinical immunology
The effect of cigarette smoking on IgE levels and circulating lymphocytes in cord blood

Wanda Karwowska

,

Jadwiga Rachtan

,

Ewa Wieczorek