Clinical immunology
The effect of the diet of pregnant women on the development of allergy at their children

The objective of this study was to investigate dietary habits and nutritional status of 67 pregnant women. The food intake was assessed by questionnaire studies. It was found out that dietary habits of pregnant women are partly adequate to the nutritional requirements and it connected both with the frequency and type of consumed products (vegetables, fruits whole-meal bread). The aim of this work was to estimation the activity of blood cells in umbilical cord of new-born children with the family atopic disease history. The analysis of umbilical cord blood showed that children from non-atopic families displayed lower IgE levels when compared with the newborns of atopic parents. The differences in serum IgE levels in umbilical blood were statistically significant. The newborns from atopic parents displayed higher IgE antibody level in umbilical blood, in comparison to the children with negative family history of atopy. Increased concentration of the immunoglobulin E in blood umbilical cord is affected by heredity or is acquired during the life-time of the fetus with tendency to the allergy. On the other hand, the differences between both groups in the migration index for b-lactoglobulin-inhibited leukocytes were highly statistically significant.