ISSN: 1230-2813
Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii
Current issue Archive Manuscripts accepted About the journal Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
1/2019
vol. 28
 
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abstract:
Case report

Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations

Przemysław Zakowicz, Paweł Wójciak, Sebastian Dziuda, Filip Rybakowski

Adv Psychiatry Neurol 2019; 28 (1): 70-77
Online publish date: 2019/03/30
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Purpose
Despite progress in the treatment of schizophrenia, treatment resistance is reported in about 30% of patients. Various forms of treatment augmentation are used, but clozapine is generally considered to be the gold standard of care. In the management of patients with clozapine resistance adjunctive electroconvulsive therapy (ECT) courses have been proposed. In recent years particular attention has been paid to augmentation of clozapine with the maintenance electroconvulsive therapy (M-ECT).

Case description
The paper presents a patient with treatment-resistant schizophrenia and chronic psychotic symptoms leading to self-destructive and suicidal behaviors. After concurrent treatment with clozapine and M-ECT her clinical status and functioning have improved.

Comment
Maintenance-ECT used to augment clozapine in drug-resistant schizophrenia seems to be a safe and promising mana¬gement option.

keywords:

schizophrenia, drug resistance, clozapine, maintenance electroconvulsive therapy

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