eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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vol. 39
Original paper

Cutaneous metastasis as the first sign of renal cell carcinoma – crossroad between literature analysis and own observations

Krzysztof Balawender
1, 2
Rafał Przybyła
Stanisław Orkisz
Agata Wawrzyniak
Dariusz Boroń
3, 4
Beniamin O. Grabarek
3, 4

  1. Clinical Department of Urology and Urological Oncology, Municipal Hospital, Rzeszow, Poland
  2. Morphological Sciences Department of Human Anatomy Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland
  3. Department of Gynecology and Obstetrics with Gynecologic Oncology, Ludwik Rydygier Memorial Specialized Hospital, Krakow, Poland
  4. Department of Histology, Cytophysiology and Embryology in Zabrze, University of Technology, Faculty of Medicine in Katowice, Poland
Adv Dermatol Allergol 2022; XXXIX (3): 553-558
Online publish date: 2021/08/02
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Metastatic disease can be observed in nearly 25% of all renal cell carcinoma cases (RCC). This can present in the skin as a late symptom of the disease or as a manifestation of an undetected, asymptomatic RCC.

To review the literature and present a case study of cutaneous metastasis in primary genitourinary malignancy, especially RCC in order to broaden the related knowledge.

Material and methods
The first stage of our work was focused on presenting the results of the literature review about cutaneous metastasis in the patients with renal cell carcinoma. Next, taking into account that this type of metastasis associated with RCC is relatively rare, we have decided to present a patient aged 68 with incidentally detected skin metastases of RCC located on the scalp.

It was diagnosed as a primary manifestation of advanced disease. Computed tomography scans showed a solid mass in the left kidney. Following surgical excision of the skin lesion, a left-side nephrectomy was performed.

Cutaneous metastases of RCC present an unfavourable prognosis, however, remission is possible subsequent to early diagnosis and appropriate surgical excision.


renal cell carcinoma, cutaneous metastasis, case report, literature review

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