eISSN: 2300-6722
ISSN: 1899-1874
Medical Studies/Studia Medyczne
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
 
3/2021
vol. 37
 
Share:
Share:
more
 
 
abstract:
Case report

Cytotoxic T lymphocytes could contribute in COVID-19-induced passing anosmia

Marcin Zaremba
1
,
Agnieszka Płusa
1
,
Agnieszka Radowicz-Chil 
1

1.
Department of Clinical and Experimental Pathology, Institute of Medical Sciences, Jan Kochanowski University, Kielce, Poland
Medical Studies/Studia Medyczne 2021; 37 (3): 258–260
Online publish date: 2021/09/30
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Several clinical reports have demonstrated a spectrum of neurological manifestations of COVID-19 patients with subsequent post-mortem neuropathological findings. The aim of the case description is to show spotty inflammatory lesions in the olfactory bulb, which could lead to passing anosmia. Microscopic examination showed severe ischaemia and microglial proliferation in the olfactory bulb region. We encountered the presence of perivascular infiltration of cytotoxic T lymphocytes (CD8). The COVID-19 pandemic brought us many new challenges concerning viral detection, transmission, abd spread, then clinical symptoms, and clinical outcome. It seems that cytotoxic T response could be a causative factor not only in respiratory tract injury but also is involved in the neural system, but further studies are required.
keywords:

anosmia, COVID-19, cytotoxic T lymphocytes

Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.