Advances in Dermatology and Allergology
eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current Issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
6/2025
vol. 42
 
Share:
Share:
Original paper

Development and validation of a predictive risk nomogram for atopic dermatitis

Jiayue Cui
1
,
Yahui Song
1
,
Qin Rui
1

  1. The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Centre of Soochow University/Centre of Clinical Laboratory and Translational Medicine, Suzhou, China
Adv Dermatol Allergol 2025; XLII (6): 585–593
Online publish date: 2026/01/12
Article file
Get citation
 
 
1. Weidinger S, Beck LA, Bieber T, et al. Atopic dermatitis. Nat Rev Dis Primers 2018; 4: 1.
2. Johnson KM, Will BM, Johnson DW. Diagnosis and management of atopic dermatitis. JAAPA 2021; 34: 32-6.
3. Ali F, Vyas J, Finlay AY. Counting the burden: atopic dermatitis and health-related quality of life. Acta Derm Venereol 2020; 100: adv00161.
4. Barbarot S, Silverberg JI, Gadkari A, et al. The family impact of atopic dermatitis in the pediatric population: results from an international cross-sectional study. J Pediatr 2022; 246: 220-6.e225.
5. Myers EM, Perche PO, Jorizzo JL, et al. Reducing costs in atopic dermatitis. Dermatol Ther 2022; 35: e15849.
6. Ramírez-Marín HA, Silverberg JI. Differences between pediatric and adult atopic dermatitis. Pediatr Dermatol 2022; 39: 345-53.
7. Schuler CFt, Billi AC, Maverakis E, et al. Novel insights into atopic dermatitis. J Allergy Clin Immunol 2023; 151: 1145-54.
8. Lu Z, Zeng N, Cheng Y, et al. Atopic dermatitis and risk of autoimmune diseases: a systematic review and meta-analysis. Allergy Asthma Clin Immunol 2021; 17: 96.
9. Gu C, Yao X, Li W. Burden of disease; the current status of the diagnosis and management of atopic dermatitis in China. J Clin Med 2023; 12: 5370.
10. Liu P, Zhao Y, Mu ZL, et al. Clinical features of adult/adolescent atopic dermatitis and chinese criteria for atopic dermatitis. Chin Med J 2016; 129: 757-62.
11. Silverberg JI, Mohawk JA, Cirulli J, et al. Burden of disease and unmet needs in atopic dermatitis: results from a patient survey. Dermatitis 2023; 34: 135-44.
12. Immunology Group CSoD. Guideline Formulation and Standardization Committee CDA. Expert consensus on standardized diagnostic terminology of dermatitis and eczematous diseases. Chin J Dermatol 2021; 11: 937-42.
13. Chiricozzi A, Levi A, Palladino C, et al. Enabling precision medicine with biomarkers of response to treatment in atopic dermatitis: where are we now? A narrative review. Front Med 2025; 12: 1574697.
14. Cheng R, Guo Y, Huang L, et al. Current status in diagnosis of atopic dermatitis in China. Allergy 2017; 72: 1277-8.
15. Wang Q, Liu L, Gao S, Su S. Guideline for diagnosis and treatment of atopic dermatitis in China (2020). Chin J Dermatol 2020; 53: 81-8.
16. Wang X, Li LF, Zhao DY, et al. Prevalence and clinical features of atopic dermatitis in China. Biomed Res Int 2016; 2016: 2568301.
17. Nie Z, Xiao R, Song J, et al. Economic burden and healthcare resource utilization of childhood atopic dermatitis in China. J Chin Pharm Sci 2024; 33: 458-69.
18. Guo Y, Zhang KY, Zou YF, et al. National situation, trends, and predictions of disease burden of atopic dermatitis in Chinese children and adolescents. Front Microbiol 2023; 14: 1161969.
19. Immunology Group, Chinese Society of Dermatology. Consensus on the whole-process management of atopic dermatitis. Chin J Dermatol 2023; 56: 5-15.
20. Dermatology CSo, Association CD. Clinical pathway for the diagnosis and treatment of moderate to severe atopic dermatitis in China (2023): an expert consensus. Chin J Dermatol 2023; 56: 1000-7.
21. Working Group for Atopic Dermatitis, Chinese Society of Dermatology; Working Group for Children′s Diseases, Chinese Society of Dermatology. Treatment of atopic dermatitis with dupilumab: an expert consensus. Chin J Dermatol 2022; 55: 465-70.
22. China Dermatologist Association; Chinese Society of Dermatology; Dermatology Branch of China International Exchange and Promotive Association for Medical and Health Care; State Key Laboratory of Complex Severe and Rare Diseases; National Clinical Research Center for Dermatologic and Immunologic Diseases. Expert consensus on the application and management of therapeutic drugs for atopic dermatitis (2024). Chin J Dermatol 2024; 57: 97-108.
23. Fishbein AB, Silverberg JI, Wilson EJ, et al. Update on atopic dermatitis: diagnosis, severity assessment, and treatment selection. J Allergy Clin Immunol Pract 2020; 8: 91-101.
24. Sroka-Tomaszewska J, Trzeciak M. Molecular mechanisms of atopic dermatitis pathogenesis. Int J Mol Sci 2021; 22: 4130.
25. Savva M, Papadopoulos NG, Gregoriou S, et al. Recent advancements in the atopic dermatitis mechanism. FBL 2024; 29; 84.
26. Avena-Woods C. Overview of atopic dermatitis. Am J Manag Care 2017; 23 (8 Suppl): S115-23.
27. Brunner PM, Guttman-Yassky E, Leung DYM. The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies. J Allergy Clin Immunol 2017; 139 (4 Suppl): S65-76.
28. Han Y, Chen Y, Liu X, et al. Efficacy and safety of dupilumab for the treatment of adult atopic dermatitis: a meta-analysis of randomized clinical trials. J Allergy Clin Immunol 2017; 140: 888.
29. Keegan AD, Leonard WJ, Zhu J. Recent advances in understanding the role of IL-4 signaling. Fac Rev 2021; 10: 71.
30. Iwaszko M, Bia³y S, Bogunia-Kubik K. Significance of interleukin (IL)-4 and IL-13 in inflammatory arthritis. Cells 2021; 10: 3000.
31. Davoine F, Lacy P. Eosinophil cytokines, chemokines, and growth factors: emerging roles in immunity. Front Immunol 2014; 5: 570.
32. Thyssen JP, Rinnov MR, Vestergaard C. Disease mechanisms in atopic dermatitis: a review of aetiological factors. Acta Derm Venereol 2020; 100: adv00162.
33. Huang TH, Chen YC, Lin SY, et al. Treatment of atopic dermatitis with dupilumab in Taiwan: dynamic changes of IgE levels as a potential response biomarker. Eur J Dermatol 2019; 29: 658-9.
34. Yang L, Fu J, Zhou Y. Research progress in atopic march. Front Immunol 2020; 11: 1907.
35. Wechsler ME, Klion AD, Paggiaro P, et al. Effect of dupilumab on blood eosinophil counts in patients with asthma, chronic rhinosinusitis with nasal polyps, atopic dermatitis, or eosinophilic esophagitis. J Allergy Clin Immunol Pract 2022; 10: 2695-709.
36. Siegfried EC, Bieber T, Simpson EL, et al. Effect of dupilumab on laboratory parameters in adolescents with atopic dermatitis: results from a randomized, placebo-controlled, phase 3 clinical trial. Am J Clin Dermatol 2021; 22: 243-55.
37. Li Z, Wang Y, Wu Y, et al. Real-world efficacy and safety of abrocitinib in Chinese atopic dermatitis patients: a single-center prospective study. Allergy 2025; 80: 1417-27.
38. Yang G, Seok JK, Kang HC, et al. Skin barrier abnormalities and immune dysfunction in atopic dermatitis. Int J Mol Sci 2020; 21: 2867.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Quick links
© 2026 Termedia Sp. z o.o.
Developed by Bentus.