eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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vol. 40
Original paper

Evaluation of the efficacy of RF microneedling and oral isotretinoin in comparison with oral isotretionoin alone in the treatment of acne vulgaris

Intisar Ahmed Hasan
Zahraa Najah Mahdi
Rana Khalid Obeed

Department of Medicine, Faculty of Medicine, University of Diyala, Baqubah, Iraq
Al-anbar Health Director, Ministry of Health, Iraq
Adv Dermatol Allergol 2023; XL (1): 111-114
Online publish date: 2023/01/16
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Acne vulgaris is one of the most common skin illnesses in teenagers, affecting 80% of people aged 11–30 years. Scars on the face are caused by high inflammation, severe acne, physical manipulation of the skin, and delayed treatment.

To compare the effectiveness and safety of an automated RF micro needlingn device and oral isotretinoin with oral isotretinon alone alone for treating active acne.

Material and methods:
A cross-sectional study of 40 moderate acne sufferers. Twenty patients with active acne were treated with an automated RF microneedling device and isotretinoin 0.5–1 mg/kg. Group B included 20 people with active acne, who were given a single dose of 0.5–1 mg/kg isotretinoin.

In this cross-sectional research, 40 acne vulgaris patients were divided into 2 groups: group A: 23.8 ±3.2 years old, 58.95 ±5.5 kg, 13 females, and 7 males. There were 15 females and 5 males in group B: 24.4 ±3.7 years old and weighing 56.4 ±8.46 kg. After 12 weeks, group A shows better global acne assessment scale (GAAS) outcomes than group B than group B. After 6 months, group A showed better results than group B. The GAAS meaning global acne assessment scale did not change after 4–8 weeks of treatment. There was no age or weight difference.

Acne vulgaris may be treated with fractional RF microneedling. Active acne treatment with RF microneedling is safe and effective, has a quicker response, causes less scarring, and reduces recurrence.


efficacy, RF microneedling, oral isotretinoin, comparison, oral isotretionoin alone, treatment, acne vulgaris

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