Journal of Contemporary Brachytherapy
eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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Original paper

Excellent local control and minimal toxicity with salvage intensity-modulated radiotherapy and high-dose-rate brachytherapy for vaginal recurrence of endometrial cancer: A 10-year retrospective analysis

Mansi Barthwal
1
,
Sheen Dube
1
,
Florence Mutua
1
,
Erin Baker
1
,
Vibhay Pareek
1
,
Aldrich T. Ong
1
,
Saranya Kakumanu
1

  1. Department of Radiation Oncology, CancerCare Manitoba, Winnipeg, MB, Canada, 2Department of Biochemistry, University of Winnipeg, Winnipeg, MB, Canada
J Contemp Brachytherapy 2025; 17, 6
DOI: https://doi.org/10.5114/jcb.2025.158425
Online publish date: 2025/12/31
Article file
- Excellent local control.pdf  [0.20 MB]
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1. Creasman WT, Odicino F, Maisonneuve P et al. Carcinoma of the corpus uteri. Int J Gynecol Obstet 2006; 95 (Suppl 1): S105-S143.
2. Jhingran A, Burke TW, Eifel PJ. Vaginal recurrence of endometrial cancer: Treatment outcomes with radiotherapy. Int J Radiat Oncol Biol Phys 2012; 82: 1837-1843.
3. Klopp AH, Mourtada F, Eifel PJ. Intensity-modulated radiotherapy in gynecologic cancers. Curr Oncol Rep 2013; 15: 218-225.
4. Nag S, Gupta N. High-dose-rate brachytherapy in gynecologic malignancies. Semin Radiat Oncol 2000; 10: 134-145.
5. Wylie J, Irwin C, Pintilie M et al. Efficacy of salvage radiotherapy for recurrent endometrial cancer. Gynecol Oncol 2000; 77: 398-404.
6. Eifel PJ, Jhingran A, Bodurka DC et al. Late effects of radiotherapy in endometrial cancer. J Clin Oncol 2005; 23: 2778-2786.
7. Miller DS, Filiaci VL, Mutch DG et al. Systemic therapy in advanced endometrial cancer: A review. J Clin Oncol 2020; 38: 1716-1725.
8. Lee JY, Kim EY, Jung KW et al. Brachytherapy outcomes in cervical cancer: A national cohort study. Radiother Oncol 2017; 125: 234-240.
9. Georg P, Lang S, Dimopoulos JC et al. Image-guided brachytherapy in gynecologic cancers. Radiother Oncol 2012; 103: 159-165.
10. Wang Z, Zhang Y, Liu X et al. Molecular profiling of recurrent cancers: Insights into mechanisms of resistance. Cancer Res 2021; 81: 890-899.
11. Morice P, Leary A, Creutzberg C et al. Endometrial cancer: ESMO clinical practice guidelines. Ann Oncol 2016; 27 (Suppl 5): v38-v46.
12. Cancer Genome Atlas Research Network; Kandoth C, Schultz N, Cherniack AD et al. Integrated genomic characterization of endometrial carcinoma. Nature 2013; 497: 67-73.
13. Oaknin A, Tinker AV, Gilbert L et al. Immunotherapy in endometrial cancer: Current landscape and future directions. J Immunother Cancer 2022; 10: e004073.
14. Beriwal S, Chen H, Smith M et al. High-dose-rate brachytherapy for vaginal recurrence of endometrial cancer. Brachytherapy 2012; 11: 247-252.
15. Petereit DG, Tannehill SP, Grosen EA et al. Toxicity of radiotherapy in endometrial cancer. Int J Radiat Oncol Biol Phys 2005; 61: 735-742.
16. Toita T, Kato S, Niibe Y et al. Image-guided brachytherapy in cervical cancer: Japanese experience. J Radiat Res 2011; 52: 1-8.
17. Pachman DR, Barton DL, Clayton AC et al. Quality of life in endometrial cancer survivors. Gynecol Oncol 2015; 138: 507-513.
18. Eskander RN, Sill MW, Beumer JH et al. Immunotherapy in endometrial cancer: Rationale and ongoing trials. Cancer Treat Rev 2023; 115: 102529.
19. Fung-Kee-Fung M, Dodge J, Elit L et al. Surveillance in endometrial cancer: Evidence-based recommendations. Int J Gynecol Cancer 2013; 23: 1485-1492.
20. Schwarz JK, Beriwal S, Esthappan J et al. Dose escalation in brachytherapy for endometrial cancer. Brachytherapy 2015; 14: 600-606.
21. Viswanathan AN, Creutzberg CL, Craighead P et al. Brachytherapy in endometrial cancer: An ASTRO evidence-based guideline. Pract Radiat Oncol 2014; 4: 21-28.
22. Jhingran A, Eifel PJ. Late toxicity of radiotherapy in gynecologic cancers. Curr Oncol Rep 2013; 15: 226-232.
23. Kitajima K, Murakami K, Yamasaki E et al. PET/CT in gynecologic cancers: Diagnostic and therapeutic implications. Eur J Nucl Med Mol Imaging 2011; 38: 1270-1282.
24. Zhang Y, Wang L, Li X et al. Machine learning in predicting cancer recurrence: A review. J Biomed Inform 2022; 126: 103986.
25. Westin SN, Sun CC, Broaddus RR et al. Quality of life in endometrial cancer: Patient-reported outcomes. Gynecol Oncol 2019; 154: 237-243.
26. Smith RA, Andrews KS, Brooks D et al. Cancer screening and prognostic factors in the United States. CA Cancer J Clin 2018; 68: 7-30.
Copyright: © 2025 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
  
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