eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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1/2010
vol. 35
 
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abstract:

Experimental immunology
The in vivo effect of Rhodiola kirilowii extracts on blood granulocytes metabolic activity in mice

Ewa Skopińska-Różewska, Małgorzata Bychawska, Beata Białas-Chromiec, Ewa Sommer, Mirosława Furmanowa, Przemysław M. Mrozikiewicz, Waldemar Buchwald, Sebastian Mielcarek, Andrzej K. Siwicki

Centr Eur J Immunol 2010; 35 (1): 20-24
Online publish date: 2010/04/06
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Rhodiola kirilowii roots and rhizomes are traditionally used in China as a tonic, adaptogen, antimicrobial and anti-inflammatory drug. The plant is also used in the Chinese medicine for the enhancement of the ability of anti-anoxia, moreover it shows anticoagulative properties and decreases the level of blood sugar. R. kirilowii also protect people against cardiopulmonary function problems when moving to high altitude (4500 m).
The aim of this work was to study the in vivo effect of aqueous and 50% hydro-alcoholic extracts of R. kirilowii roots on metabolic activity of blood granulocytes in mice. Hydro-alcoholic extract of R. kirilowii exerted stimulatory effect in the lowest and in the highest dose applied. No difference from the control was observed in the group fed intermediate doses. In the case of aqueous extract intermediate doses presented inhibition of granulocytes chemiluminescence.
keywords:

mice, Rhodiola kirilowii, granulocytes, chemiluminescence

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