eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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1/2009
vol. 34
 
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abstract:

Experimental immunology
The in vivo effect of Rhodiola rosea and Rhodiola quadrifida hydro-alcoholic extracts on chemokinetic activity of spleen lymphocytes in mice

Ewa Skopińska-Różewska
,
Małgorzata Bychawska
,
Beata Białas-Chromiec
,
Ewa Sommer

Centr Eur J Immunol 2009; 34 (1): 42-45
Online publish date: 2009/03/31
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Rhodiola rosea (RR) and Rhodiola quadrifida (RQ) roots and rhizomes are traditional natural drugs used in Asia as adaptogens and antidepressants. The aim of this work was to study the in vivo effect of 50% hydro-alcoholic extracts of RR and RQ roots and rhizomes on the ex vivo chemokinetic activity of splenic lymphocytes in mice. Mice were fed for 7 days Rhodiola extracts in daily doses 40 or 200 mg. The chemokinetic activity of splenocytes was determined in 24-hour cell cultures in capillary tubes. Both extracts stimulated splenocytes mobility in lower dose, in higher dose (200 mg) only RQ extract was effective.
keywords:

Rhodiola rosea, Rhodiola quadrifida, mice, splenocytes, chemokinesis

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