eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
4/2015
vol. 66
 
Share:
Share:
more
 
 
abstract:
Original paper

Expression of β-catenin and its correlation with metastatic progression of esophagogastric junction adenocarcinoma

Janusz Wlodarczyk
,
Lucyna Rudnicka-Sosin
,
Jarosław Kużdżał

Pol J Pathol 2015; 66 (4): 414-419
Online publish date: 2016/02/05
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
The evaluation of β-catenin expression in adenocarcinoma of the esophagogastric junction and its influence on cancer progression.

Sixty-one patients who were diagnosed with adenocarcinoma of the esophagogastric junction were examined. We evaluated β-catenin distribution in the cell membrane and the cell nucleus in adenocarcinoma of the esophagogastric junction type 1 and type 3.

Our findings showed lack of a statistically significant difference in evaluation of adenocarcinoma type 1 and type 3 aggressiveness. However, we found a statistically significant association with the T and N stage, although we did not find an effect of them on patient survival.

Patients with cellular membrane and cell nucleus staining comprise a group of patients with higher risk of malignancy progression in adenocarcinoma of the esophagogastric junction types 1 and 3.
keywords:

β-catenin, esophago-gastric junction, adenocarcinoma

FEATURED PRODUCTS
Quick links
© 2019 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe