Genetic factors in pathogenesis of rheumatoid arthritis

Magdalena Ostanek; Andrzej Ciechanowicz

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

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3/2009
vol. 47

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abstract:

Review paper

Genetic factors in pathogenesis of rheumatoid arthritis

Magdalena Ostanek

,

Andrzej Ciechanowicz

Reumatologia 2009; 47, 3: 143–150

Online publish date: 2009/08/11

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Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder. The course of RA and its prognosis are variable. It may develop and progress slowly or rapidly causing disability and even mortality. The etiology of RA is unknown, but it is thought to have genetic and environmental basis. Familial aggregation of RA allow to suppose, that genetic factors appear to play a major role that can cause disease initiation.

keywords:

rheumatoid arthritis, gene, polymorphism

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Genetic factors in pathogenesis of rheumatoid arthritis

Magdalena Ostanek , Andrzej Ciechanowicz

rheumatoid arthritis, gene, polymorphism

Magdalena Ostanek

,

Andrzej Ciechanowicz