eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
5/2018
vol. 35
 
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abstract:
Original paper

HIV infection and sex in sex-on-premises venues are associated with a higher risk of syphilis reinfection among men who have sex with men

Maciej Pastuszczak, Monika Bociąga-Jasik, Marek Sitko, Anna Wojas-Pelc

Adv Dermatol Allergol 2018; XXXV (5): 481-484
Online publish date: 2018/07/19
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Introduction
Recent outbreaks of syphilis occurred predominantly in men who have sex with men (MSM). A significant proportion of syphilis cases occur in MSM who had more than one episode of syphilis. This group may play an important role in syphilis transmission.

Aim
To identify factors associated with the risk of syphilis reinfection.

Material and Methods
Forty-four MSM patients with the first episode of syphilis who were treated at the Department of Dermatology at the Jagiellonian University School of Medicine in Krakow, Poland were included in this study. After completing the treatment, the RPR testing was done every 3 months for 2 years in every patient. In the study period, we identified 12 (22%) cases of syphilis reinfection, eight of which were asymptomatic. Clinical, demographic and behavior data from patients with only one episode of syphilis were compared with those collected from repeaters.

Results
Individuals with syphilis reinfection had concomitant HIV infection more frequently, reported a higher number of sexual partners and had sex in sex on premises venues more frequently (p < 0.05). In the multivariate analysis, we found that being HIV-infected MSM and having sex in sex on premises venues independently correlated with a higher risk of syphilis reinfection (OR = 9.6, 95% CI: 2.2–42.5 and OR = 5.6, 95% CI: 1.4–22.5, respectively).

Conclusions
Results of our study highlight a strong need for frequent and repeated screening among MSM patients (especially those with concomitant HIV infection) with the first episode of syphilis and taking detailed patient’s history regarding also demographic and behavior data. We should also improve prevention policies to reduce risk behaviors in this population.

keywords:

syphilis, HIV, sexual behavior

references:
European Centre for Disease Prevention and Control (ECDC). Sexually transmitted infections in Europe 2011. Stockholm: ECDC; 2013. Available from: http://ecdc.europa.eu/en/publications/Publications/sexually-transmitted-infections-europe-surveillance-report-2012.pdf.
Kenyon C, Lynen L, Florence E, et al. Syphilis reinfections pose problems for syphilis diagnosis in Antwerp, Belgium – 1992 to 2012. Euro Surveill 2014; 19: pii20958.
Katz KA, Lee MA, Gray T, et al. Repeat syphilis among men who have sex with men – San Diego County, 2004-2009. Sex Transm Dis 2011; 38: 349-52.
Brewer TH, Peterman TA, Newman DR, et al. Reinfections during the Florida syphilis epidemic, 2000-2008. Sex Transm Dis 2011; 38: 12-7.
Abara WE, Hess KL, Neblett Fanfair R, et al. Syphilis trends among men who have sex with men in the United States and Western Europe: a systematic review of trend studies published between 2004 and 2015. PLoS One 2016; 11: e0159309.
Pastuszczak M, Wojas-Pelc A. Current standards for diagnosis and treatment of syphilis: selection some practical issues, based on the European (IUSTI) and U.S. (CDC) guidelines. Postep Dermatol Alergol 2013; 30: 203-10.
Phipps W, Kent C, Kohn R, et al. Risk factors for repeat syphilis in men who have sex with men. San Francisco. Sex Transm Dis 2009; 36: 331-5.
Cohen SE, Chew Ng RA, Katz KA, et al. Repeat syphilis among men who have sex with men in California, 2002-2006: implications for syphilis elimination efforts. Am J Public Health 2012; 102: e1-8.
Hourihan M, Wheeler H, Houghton R, et al. Lessons from the syphilis outbreak in homosexual men in east London. Sex Transm Infect 2004; 80: 509-11.
Morgan CA, Lukehart SA, Van Voorhis WC. Protection against syphilis correlates with specificity of antibodies to the variable regions of Treponema pallidum repeat protein K.
Infect Immun 2003; 71: 5605-12.
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