eISSN: 2391-6052
ISSN: 2353-3854
Alergologia Polska - Polish Journal of Allergology
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1/2018
vol. 5
 
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abstract:
Guidelines/recommendations

Introduction to management of drug hypersensitivity. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology

Marek L. Kowalski
,
Grażyna Bochenek
,
Anna Bodzenta-Łukaszyk
,
Joanna Glück
,
Michał Kurek
,
Marita Nittner-Marszalska
,
Grzegorz Porębski
,
Iwona Poziomkowska-Gęsicka
,
Barbara Rymarczyk
,
Grażyna Sławeta
,
Małgorzata Wiśniewska
,
Joanna Makowska

Alergologia Polska – Polish Journal of Allergology 2018; 5, 1: 3–9
Online publish date: 2018/03/23
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Drug hypersensitivity reactions are a real challenge for allergologist practitioners. Variety of symptoms evoked by drugs and different pathomechanisms of the reactions make the diagnosis sometimes very difficult and the clinical thinking requires deep understanding of underlying immunological pathomechanisms. Moreover the new drug classes introduced to the treatment are evoking novel types of hypersensitivity reactions. The detailed clinical history is crucial to choose the proper way of further testing. In the case of confirmation of hypersensitivity reaction, the further step is to find the safe alternatives for culprit drug to desensitize the patient (if the culprit drug is unchangeable).
keywords:

drug hypersensitivity, diagnostics, safe drugs, desensitization





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