Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update

Katarzyna Chyl-Surdacka; Adam Borzęcki; Jakub Latifa; Monika Turska-Kozłowska; Marianna Majchrzycka

doi:10.5114/ada.2022.124344

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Review paper

Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update

Katarzyna Chyl-Surdacka

¹

,

Adam Borzęcki

¹

,

Jakub Latifa

¹

,

Monika Turska-Kozłowska

^{1, 2}

,

Marianna Majchrzycka

³

Department of Dermatology, Non-Public Health Care Center ‘Med-Laser’, Lublin, Poland

Department of Molecular Biology, The John Paul II Catholic University of Lublin, Lublin, Poland

Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland

Adv Dermatol Allergol 2023; XL (3): 337–340

DOI: https://doi.org/10.5114/ada.2022.124344

Online publish date: 2023/01/19

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AMA

Chyl-Surdacka K, Borzęcki A, Latifa J, Turska-Kozłowska M, Majchrzycka M. Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2023;40(3):337-340. doi:10.5114/ada.2022.124344.

APA

Chyl-Surdacka, K., Borzęcki, A., Latifa, J., Turska-Kozłowska, M.,  & Majchrzycka, M. (2023). Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 40(3), 337-340. https://doi.org/10.5114/ada.2022.124344

Chicago

Chyl-Surdacka, Katarzyna, Adam Borzęcki, Jakub Latifa, Monika Turska-Kozłowska,  and Marianna Majchrzycka. 2023. "Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 40 (3): 337-340. doi:10.5114/ada.2022.124344.

Harvard

Chyl-Surdacka, K., Borzęcki, A., Latifa, J., Turska-Kozłowska, M.,  and Majchrzycka, M. (2023). Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 40(3), pp.337-340. https://doi.org/10.5114/ada.2022.124344

MLA

Chyl-Surdacka, Katarzyna et al. "Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 40, no. 3, 2023, pp. 337-340. doi:10.5114/ada.2022.124344.

Vancouver

Chyl-Surdacka K, Borzęcki A, Latifa J, Turska-Kozłowska M, Majchrzycka M. Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2023;40(3):337-340. doi:10.5114/ada.2022.124344.

Darier disease is one of the most common genodermatoses. Although Darier disease was described in 1886, targeted therapies remain unknown. Current literature lacks specific guidelines for treatment of Darier disease. Treatment remains symptomatic and may be challenging for dermatologists. The aim of this article is to present clinical characteristics and treatment options. In a mild form of the disease with a small number of skin lesions, the symptoms can be reduced by the use of topical medications. Oral retinoids, alternatively doxycycline, seem to be beneficial in extensive and persistent lesions unresponsive to local treatment. In limited, hypertrophic forms, surgical methods, laser therapy and photodynamic therapy could be used.

keywords:

Keratosis follicularis (Darier disease) – clinical characteristics and treatment – a review and update

Katarzyna Chyl-Surdacka 1 , Adam Borzęcki 1 , Jakub Latifa 1 , Monika Turska-Kozłowska 1, 2 , Marianna Majchrzycka 3

keratosis follicularis, Darier disease

Katarzyna Chyl-Surdacka

¹

,

Adam Borzęcki

¹

,

Jakub Latifa

¹

,

Monika Turska-Kozłowska

^{1, 2}

,

Marianna Majchrzycka

³