OPTIMIZATION OF PHARMACOTHERAPY SYSTEM FOR TREATMENT OF THYROID DISEASES IN UKRAINE

Background. Recent years thyroid diseases are attracting considerable attention. On one hand, this is due to the fact that thyroid is actively reacts on environment, followed by appearance of various diseases. On the other hand, in current conditions population remains face to face with adverse impact of environment because an effective experience of the world community to fight against iodine deficiency is not implemented in Ukraine. Thus every year becomes more patients with thyroid pathology. So there becomes a need to optimize the system of healthcare provision for these patients.

Material and methods. We have analyzed medications listed in Ukrainian National Formulary and studied the dynamics of its formation. A comparative analysis of UNF with the British National Formulary was conducted. The compliance of UNF with the WHO Model List of Essential Medicines was checked.

Results. Comparative analysis of assortment dynamic of UNF medications for treatment and

prevention of thyroid diseases showed that foreign drugs had an advantage of inclusion to

formulary. The main difference between BNF and UNF is that drugs are brought in BNF only by original name. In UNF antithyroid drugs are presented by thiamazole which is absent in WHO Model List of Essential Medicines and BNF.

Conclusions. We recommend to provide arguments concerning evidence of clinical and cost

effectiveness of drugs included to UNF; to include drugs in UNF exclusively by original name; to include carbimazole and propylthiouracil medications into group of antithyroid drugs in UNF; to unite subsections 7.3.2 and 7.3.3 of UNF to one general subsection “antithyroid drugs”.