Omalizumab improves forced expiratory volume in 1 second in patients with severe asthma

Krzysztof Pałgan; Magdalena Żbikowska-Götz; Kinga Lis; Elżbieta Chrzaniecka; Zbigniew Bartuzi

doi:10.5114/ada.2018.77241

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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5/2018
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abstract:

Original paper

Omalizumab improves forced expiratory volume in 1 second in patients with severe asthma

Krzysztof Pałgan

,

Magdalena Żbikowska-Götz

,

Kinga Lis

,

Elżbieta Chrzaniecka

,

Zbigniew Bartuzi

Adv Dermatol Allergol 2018; XXXV (5): 495-497

DOI: https://doi.org/10.5114/ada.2018.77241

Online publish date: 2018/07/19

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Introduction
Asthma is a multiphenotypic disease, and therapeutic managenment in patients with severe asthma is particulary difficult, with conventional treatment of severe asthma showing poor efficacy.

Aim
To analyse forced expiratory volume in 1 s (FEV1) following the adminstration of omalizumab.

Material and methods
Six patinents (mean age: 50 ±12.6) with severe, uncontrolled asthma according to the GINA guidelines were enrolled in the study.

Results
Treatment with omalizumab increased in all subjects FEV1 by 17.28 ±13.4% after months and 18.57 ±13.4% after 12 months of treatment.

Conclusions
These results provides further evidence that therapy with omalizumab improves spiromtric parameters in severe asthma.

keywords:

Omalizumab improves forced expiratory volume in 1 second in patients with severe asthma

Krzysztof Pałgan , Magdalena Żbikowska-Götz , Kinga Lis , Elżbieta Chrzaniecka , Zbigniew Bartuzi

asthma, omalizumab, spirometry, forced expiratory volume in 1 s

Krzysztof Pałgan

,

Magdalena Żbikowska-Götz

,

Kinga Lis

,

Elżbieta Chrzaniecka

,

Zbigniew Bartuzi