eISSN: 1509-572x
ISSN: 1641-4640
Folia Neuropathologica
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
3/2011
vol. 49
 
Share:
Send email
Share:
abstract:

Original article
Some markers of neuronal damage in cerebrospinal fluid of multiple sclerosis patients in relapse

Krystyna Mitosek-Szewczyk
,
Wanda Gordon-Krajcer
,
Dorota Flis
,
Zbigniew Stelmasiak

Folia Neuropathol 2011; 49 (3): 191-196
Online publish date: 2011/09/30
View full text Get citation
 
In this paper the performance of cerebrospinal fluid (CSF) protein biomarkers important for monitoring damage of brain astrocytes and neurons for MS is reviewed. We estimated neurofilament, tau and phospho-tau proteins, β-APP, Aβ, S-100B and neuron-specific enolase in CSF of MS patients during relapse. We noted elevation of neurofilament, tau and phospho-tau proteins, S-100B, neuron-specific enolase and c-terminal epitopes of β-APP; concomitantly decrease of Aβ was observed. These CSF biomarkers for MS relapse should reflect the central pathoge­nic processes in the brain, i.e., axonal and neuronal degeneration.
keywords:

multiple sclerosis, neurofilament, tau and phospho-tau proteins, S-100B, β-APP, Aβ-amyloid protein, neuron-specific enolase
FEATURED PRODUCTS
BOOKS
• Wprowadzenie do neurologopedii Wydanie II zaktualizowane
EVENTS
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.