Paradoxical bronchoconstriction due to salbutamol MDI

Sindhu Chitikela; Animesh Ray; Sanjeev Sinha

doi:10.5114/pja.2018.74454

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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abstract:

Case report

Paradoxical bronchoconstriction due to salbutamol MDI

Sindhu Chitikela

,

Animesh Ray

,

Sanjeev Sinha

Alergologia Polska – Polish Journal of Allergology 2018; 5, 1: 62–66

DOI: https://doi.org/10.5114/pja.2018.74454

Online publish date: 2018/03/23

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An 18-year-old female student presented to us with a history of episodes of nocturnal shortness of breath, precipitated on exposure to cold, for a duration of 6 years. Suspecting it to be due to bronchial asthma, the patient was subjected to spirometry. Pre-bronchodilator spirometry revealed abnormal pulmonary function, suggestive of obstructive lung disease. Postbronchodilator spirometry with a salbutamol metered-dose inhaler (MDI) showed a further decrease in pulmonary function, suggestive of bronchoconstriction. In such cases, it may lead to an erroneous diagnosis of chronic obstructive pulmonary disease or an inappropriate clinical response, leading to therapeutic implications. Here we report a case of a bronchial asthma patient showing paradoxical bronchoconstriction following use of a salbutamol metered-dose inhaler.

keywords:

Paradoxical bronchoconstriction due to salbutamol MDI

Sindhu Chitikela , Animesh Ray , Sanjeev Sinha

astma, paradoksalny skurcz oskrzeli

Sindhu Chitikela

,

Animesh Ray

,

Sanjeev Sinha