eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
Current issue Archive Special issues Subscription
SCImago Journal & Country Rank

 
4/2009
vol. 5
 
Share:
Share:
more
 
 
abstract:

Physical development and pulmonary function in children and adolescents treated at two cystic fibrosis treatment centres in Poland

Wioleta Umławska
,
Monika Rams

Arch Med Sci 2009; 5, 4: 583-588
Online publish date: 2009/12/30
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction: Delayed physical development, delayed puberty and malnutrition are common in children suffering from cystic fibrosis
Material and methods: Physical development and respiratory function were assessed in 33 children and adolescents with cystic fibrosis treated at two cystic fibrosis treatment centres in Poland.
Results: Mean body height and body weight were significantly lower in the study group than in the reference population. Eightteen percent of the patients had severe developmental problems, and had body heights that were more than two standard deviations below the mean for the reference population. Over 60% of the patients were malnourished, and a third of these were severely malnourished. Mean leg length was considerably lower in the study group than in the reference population. The children with cystic fibrosis had infantile body proportions. Chest depth was higher and chest width was lower in the study group than in the reference population. Predicted FVC, predicted FEV1 and predicted FEF25-75 were lower in the study group than in the reference population. There was a strong positive correlation between nutritional status and predicted FEV1. On the other hand, there was no clear correlation between the type of CFTR gene mutation or infection caused by Pseudomonas aeruginosa and predicted FEV1.
Conclusions: A full-scale study is underway to determine the effect of the type of CFTR gene mutation and infection caused by P. aeruginosa on pulmonary function in children with cystic fibrosis treated at specialized care facilities in Poland.
keywords:

children, cystic fibrosis, growth, body proportions, spirometric measurements

Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe