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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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3/2008
vol. 110
 
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abstract:
Original paper

Posterior polymorphous dystrophy – changes in corneal morphology in confocal microscopy

Jacek P. Szaflik
1, 2
,
Urszula Kołodziejska
1, 2
,
Monika Udziela
1, 2
,
Wojciech Kołodziejczyk
1, 2
,
Jerzy Szaflik
1, 2

  1. Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Uniwersytetu Medycznego w Warszawie
  2. Z Samodzielnego Publicznego Klinicznego Szpitala Okulistycznego w Warszawie
Online publish date: 2008/09/15
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Purpose: To describe the in vivo confocal microscopic findings in posterior polymorphous dystrophy (PPD).

Material and methods: Eleven patients (22 eyes) with PPD suspected or clinically diagnosed were examined using scanning slit

white light confocal microscopy (ConfoScan 3, Nidek Technologies).

Results: Endothelial cell densities ranged from 716 to 2380 cells/mm2 and endothelial polymegathism was noted in all cases. In

5 cases PPD changes was reported unilateral. Confocal microscopy demonstrated a variety of vesicular and linear abnormalities.

In 13 eyes exhibited bright, nucleus-like structures within endothelial cells. Stromal edema was noted in 4 cases.

Conclusions: To our knowledge, we present the largest case series of PPD imaged by in vivo confocal microscopy. Confocal

microscopy images of PPD are very characteristic. This method allows to confirm presumptive or to identify final diagnosis. Our

study enhances the value of confocal microscopy in detection and monitoring corneal abnormalities.
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