Polish Journal of Pathology

Abstract

3/2013 vol. 64

Primary mucoepidermoid carcinoma of the breast: a case report with immunohistochemical analysis and comparison with salivary gland mucoepidermoid carcinomas

Maria Heloisa Rached Palermo
,
Michelli Bárbara Pinto
,
Juliana Silva Zanetti
,
Alfredo Ribeiro-Silva
Pol J Pathol 2013; 64 (3): 210-215
DOI: https://doi.org/10.5114/pjp.2013.38141
Online publish date: 2013/10/21
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Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
Mucoepidermoid carcinomas in mammary glands represent 0.3% of all breast tumors. Features of salivary gland mucoepidermoid carcinoma have been used in studies concerning mucoepidermoid carcinomas of the breast because both share similar morphologic and molecular features. We report a case of primary mucoepidermoid carcinoma of the breast with an immunohistochemistry staining panel. We verified that MUC5AC occurs in more than 50% of high-grade tumors, and MUC1 correlates with shorter disease-free survival. The comparative analysis of mucin profiles may provide further insights into the clinical behavior of these tumors.

Keywords

breast carcinoma, mucoepidermoid, immunohistochemistry, mucins, hormonal receptors

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