Retinal degenerative diseases – mechanisms 
and perspectives of treatment

Robert Rejdak; Małgorzata Szkaradek; Maciej Czepita; Wesam Taslaq; Aneta Lewicka-Chomont; Paweł Grieb

eISSN: 2719-3209
ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica

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4/2012
vol. 114

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abstract:

Review article

Retinal degenerative diseases – mechanisms and perspectives of treatment

Robert Rejdak

¹

,

Małgorzata Szkaradek

²

,

Maciej Czepita

³

,

Wesam Taslaq

²

,

Aneta Lewicka-Chomont

²

,

Paweł Grieb

⁴

Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland
Department of Ophthalmology, F. Chopin Specialised Hospital in Rzeszów, Rzeszów, Poland
Department of Ophthalmology, Pomeranian Medical University, Szczecin, Poland
Department of Experimental Pharmacology, Polish Academy of Science Medical Research Centre, Warsaw, Poland

Online publish date: 2012/12/12

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Retinal degenerative diseases are an extensive group of ocular diseases, leading to vision disorders and finally irreversible vision loss. They are an significant problem, because degenerative processes exist in common ocular disorders like glaucoma or age-related macular degeneration and many other less frequently occurring disorders. In this article, we present mechanisms leading to retinal degeneration like excitotoxicity, oxidative stress, inflammation and summarize the latest reports concerning neuroprotection in the treatment of retina degenerative diseases.

keywords:

Retinal degenerative diseases – mechanisms and perspectives of treatment

Robert Rejdak 1 , Małgorzata Szkaradek 2 , Maciej Czepita 3 , Wesam Taslaq 2 , Aneta Lewicka-Chomont 2 , Paweł Grieb 4

retinal degenerative diseases, neuroprotection, excitotoxicity, oxidative stress

Robert Rejdak

¹

,

Małgorzata Szkaradek

²

,

Maciej Czepita

³

,

Wesam Taslaq

²

,

Aneta Lewicka-Chomont

²

,

Paweł Grieb

⁴