Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years

Paweł Gerard Piotrowski; Michał Teodor Jeleń

doi:10.5114/pjp.2024.135828

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

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1/2024
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abstract:

Original paper

Retrospective analysis of negative cytology results correlated with a positive high-risk in the human papillomavirus result and subsequent results of patients over a period of three years

Paweł Gerard Piotrowski

¹

,

Michał Teodor Jeleń

²

Lab Path Experts, Koziegłowy, Poland

Departament of Immunopathology and Molecular Biology, Medical University, Wrocław, Poland

Pol J Pathol 2024; 75 (1): 36-39

DOI: https://doi.org/10.5114/pjp.2024.135828

Online publish date: 2024/02/29

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AMA

Piotrowski P, Jeleń M. Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years. Polish Journal of Pathology. 2024;75(1):36-39. doi:10.5114/pjp.2024.135828.

APA

Piotrowski, P.,  & Jeleń, M. (2024). Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years. Polish Journal of Pathology, 75(1), 36-39. https://doi.org/10.5114/pjp.2024.135828

Chicago

Piotrowski, Paweł Gerard,  and Michał Teodor Jeleń. 2024. "Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years". Polish Journal of Pathology 75 (1): 36-39. doi:10.5114/pjp.2024.135828.

Harvard

Piotrowski, P.,  and Jeleń, M. (2024). Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years. Polish Journal of Pathology, 75(1), pp.36-39. https://doi.org/10.5114/pjp.2024.135828

MLA

Piotrowski, Paweł Gerard et al. "Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years." Polish Journal of Pathology, vol. 75, no. 1, 2024, pp. 36-39. doi:10.5114/pjp.2024.135828.

Vancouver

Piotrowski P, Jeleń M. Retrospective analysis of negative cytology results
correlated with a positive high-risk in the human
papillomavirus result and subsequent results
of patients over a period of three years. Polish Journal of Pathology. 2024;75(1):36-39. doi:10.5114/pjp.2024.135828.

PlumX metrics:

This research paper evaluates the efficacy of co-testing in precluding cervical cancer, with a particular focus on distinguishable outcomes of the human papillomavirus (HPV) vs. cytology tests.

A retrospective review of 5948 patients, who tested positive for high-risk HPV but showed negative cytologic findings, revealed that 15.006% tested positive in subsequent screenings.

A comparative analysis of various commercial HPV tests highlighted the precision of mRNA-based HPV testing by Aptima (Hologic) in reducing the likelihood of false-negative cytology.

The paper challenges the conviction that a negative cytology alone suffices advocating for a condensed testing interval in instances of positive HPV outcomes, thereby facilitating earlier intervention and optimal preventive care. These findings unveil an exigency for reconsidering preventive strategies based on test outcomes.

keywords:

cervical cancer, co-testing, cytology tests, HPV, efficacy, retrospective review, high-risk HPV, mRNA-based HPV testing, false-negative cytology, preventive care

Retrospective analysis of negative cytology results correlated with a positive high-risk in the human papillomavirus result and subsequent results of patients over a period of three years

Paweł Gerard Piotrowski 1 , Michał Teodor Jeleń 2

cervical cancer, co-testing, cytology tests, HPV, efficacy, retrospective review, high-risk HPV, mRNA-based HPV testing, false-negative cytology, preventive care

Paweł Gerard Piotrowski

¹

,

Michał Teodor Jeleń

²