eISSN: 2084-9885
ISSN: 1896-6764
Neuropsychiatria i Neuropsychologia/Neuropsychiatry and Neuropsychology
Current issue Archive Manuscripts accepted About the journal Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
1/2011
vol. 6
 
Share:
Share:
more
 
 
abstract:

Review article
Frontal syndrome in schizophrenia and frontotemporal dementia: diagnostic and therapeutic implications

Jan Jaracz
,
Janusz Rybakowski

Neuropsychiatria i Neuropsychologia 2011; 6, 1: 18–24
Online publish date: 2011/07/14
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
The prefrontal cortex in humans plays a pivotal role in higher brain functions such as executive functions, working memory, action planning, decision making and processing of emotional signals. Its dysfunction may lead to significant deterioration of behaviour manifesting with symptoms of “frontal syndrome”. Evidence from neuropsychological and neuroimaging studies suggests the involvement of prefrontal cortex disturbance in schizophrenia. Structural and functional abnormalities of the prefrontal cortex are considered as an underlying cause of negative symptoms. Frontotemporal dementia (FTD) is a neurodegenerative disorder which results from frontotemporal lobar degeneration. It manifests with development of neuropsychiatric symptoms. Since diverse conditions may cause alterations in prefrontal cortex functioning, manifestations of these disorders may overlap. These similarities may lead to diagnostic problems particularly in cases with early onset FTD and schizophrenia with predominant negative symptomatology.
keywords:

frontal syndrome, schizophrenia, negative symptoms, frontotemporal dementia

Quick links
© 2019 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe