Review paper<br>Immunonutrition and lipopolysaccharide – induced Toll-like receptor signaling

Robert Słotwiński; Sylwia M. Słotwińska; Barbara J. Bałan; Sylwia Kędziora

eISSN: 1644-4124
ISSN: 1426-3912

Central European Journal of Immunology

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors

Editorial System

Submit your Manuscript

2/2009
vol. 34

Send email

Copy url:

abstract:

Review paper
Immunonutrition and lipopolysaccharide – induced Toll-like receptor signaling

Robert Słotwiński

,

Sylwia M. Słotwińska

,

Barbara J. Bałan

,

Sylwia Kędziora

Centr Eur J Immunol 2009; 34 (2): 137-142

Online publish date: 2009/05/20

View full text Get citation

Septic infections in malnourished surgical patients show the highest morbidity and mortality rate. The attempt to correct the postoperative immune and nutritional disorders by introducing immunomodulating nutrition is a promising way of improving outcome, but as yet little is known about the mechanisms of correcting postoperative extensive inflammatory response (SIRS) to a massive infection using this type of nutrition. A significant role in innate antibacterial and inflammatory response play Toll-like receptors that recognize PAMPs-pathogen-associated molecular patterns. In this paper special emphasis was put on clinical trials and the research result for TLR-dependent immune response, anti-bacterial/anti-inflammatory response applying immunonutrition with increased concentrations of glutamine and unsaturated fatty acids.

keywords:

Review paperImmunonutrition and lipopolysaccharide – induced Toll-like receptor signaling

Robert Słotwiński , Sylwia M. Słotwińska , Barbara J. Bałan , Sylwia Kędziora

immunonutrition, toll-like receptors, sepsis

Review paper
Immunonutrition and lipopolysaccharide – induced Toll-like receptor signaling

Robert Słotwiński

,

Sylwia M. Słotwińska

,

Barbara J. Bałan

,

Sylwia Kędziora