eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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vol. 31

Review paper
Severe skin complications in patients treated with antidepressants: a literature review

Marta Herstowska
Olivia Komorowska
Wiesław J. Cubała
Katarzyna Jakuszkowiak-Wojten
Maria Gałuszko-Węgielnik
Jerzy Landowski

Postep Derm Alergol 2014; XXXI, 2: 92–97
Online publish date: 2014/04/22
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Clinical manifestations of drug-induced skin reactions include a wide range of symptoms, from mild drug-induced exanthemas to dangerous and life-threatening generalized systematic reactions. Adverse drug reactions of low risk include phenomena such as drug-induced rashes, phototoxic reactions, eczemas and urticarias, which appear most often when the medication is being introduced. Drug-induced skin reactions to psychotropic medication are usually associated with antiepileptic drugs. However, a significant role can be assigned to selective serotonin reuptake inhibitors. The aim of this paper is to review a spectrum of severe skin complications in patients treated with antidepressants with the indication of their clinical monitoring and management.

adverse drug reactions, drug hypersensitive syndrome, antidepressants, selective serotonin reuptake inhibitors

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