SKIN ANALYSIS BEFORE AND AFTER TREATMENT WITH PLATELET-RICH PLASMA AND FIBRIN

Background
Today, aesthetic medicine encompasses various subfields, including regenerative medicine. The goal of regenerative therapy is not only to improve the skin’s appearance aesthetically but also to stimulate natural repair mechanisms, such as collagen and elastin synthesis and tissue regeneration, which contribute to long-lasting results and improved skin health. One of the fundamental treatments in this field is platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) therapy. The aim of this study is to analyze the skin before and after treatment with PRP and PRF and to determine the series of cascading changes occurring in the skin.

Material and methods
A retrospective analysis of photographs of 35 women taken before and after single PRP and PRF treatment was conducted. The images were captured using the Observ 520x device. Mathematical measurements of changes in the images were performed using ImageJ software. The Global Aesthetic Improvement Scale (GAIS) was used to evaluate the changes observed in the photographs after the procedure.

Results
Based on mathematical parameters obtained from the ImageJ program, vascularity, and skin tone were compared. A paired t-test indicated a statistically significant improvement in the study group in the following areas: forehead discoloration, right cheek discoloration, left cheek discoloration, forehead vascularity, and left cheek vascularity.

Conclusions
The use of PRP and PRF in aesthetic medicine is an effective treatment that delivers the expected results.