Abstract
6/2025
vol. 17
Original paper
Selection of hybrid applicators for adaptive cervical cancer brachytherapy: A practical guide
- Department of Radiation Oncology, West Virginia University Cancer Institute, Morgantown, WV, USA
- Radiation Oncology, American Oncology Institute, Hyderabad, India
- Division of Radiation Oncology, Allegheny Health Network Cancer Institute, Pittsburgh, Pennsylvania, USA
- Varian Medical Systems, Palo Alto, California, USA
J Contemp Brachytherapy 2025; 17, 6: 390–399
Online publish date: 2025/12/18
Image-based adaptive brachytherapy (IGABT) is now the standard of care for patients with locally advanced cervical cancer. EMBRACE-2 MRI-based brachytherapy study demonstrated improved local control rates and reduced morbidity using hybrid applicators. Utilization of these hybrid applicators in gynecological brachytherapy offers advantages over conventional interstitial techniques; however, practical guidance for applicator selection based on disease extent and image findings remains limited.
This manuscript aimed to provide a practical framework for applicator selection based on five case scenarios to demonstrate optimal applicator selection tailored to disease extent and anatomical considerations.
This manuscript aimed to provide a practical framework for applicator selection based on five case scenarios to demonstrate optimal applicator selection tailored to disease extent and anatomical considerations.
Keywords
brachytherapy, cervical cancer, hybrid applicators, image-based adaptive brachytherapy
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