Advances in Psychiatry and Neurology
eISSN: 2720-5371
ISSN: 1230-2813
Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii
Current issue Archive Manuscripts accepted About the journal Scientific board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
4/2025
vol. 34
 
Share:
Share:
Case report

Successful invasive treatment of stroke in a patient with a left ventricle assist device – case report

Anna Konopka
1
,
Halina Sienkiewicz-Jarosz
2
,
Marzena Ułamek-Kozioł
2
,
Małgorzata Misztal-Ogonowska
3
,
Elżbieta Smaga
4
,
Ilona Michałowska
5

  1. Department of Intensive Cardiac Therapy, National Institute of Cardiology, Warsaw, Poland
  2. 1st Neurological Department, Institute of Psychiatry and Neurology, Warsaw, Poland
  3. Department of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland
  4. Neurology Consultant, National Institute of Cardiology, Warsaw, Poland
  5. Department of Radiology, National Institute of Cardiology, Warsaw, Poland
Adv Psychiatry Neurol 2025; 34 (4)
Online publish date: 2025/12/10
Article file
Get citation
 
PlumX metrics:
 
1. Stone ME, Golhar SY, Baronos S. Durable mechanical circulatory assist devices for heart failure. In: Kaplan JA, Augoustides JG, Gutsche JT, Maus T, Mittnacht AJC, Pagel PS, Ramakrishna H (eds.). Kaplan’s Cardiac Anesthesia: Perioperative and Critical Care Management. 8th ed. Philadelphia, PA: Elsevier; 2023, p. 823-841.
2. Plecash AR, Byrne D, Flexman A, Toma M, Field TS. Stroke in patients with left ventricular assist devices. Cerebrovasc Dis 2022; 51: 3-13.
3. Ibeh Ch, Melmed KR, Yuzefpolskaya M, Colombo PC, Willey JZ. Stroke epidemiology and outcomes in the modern era of left ventricular assist devices. Heart Fail Rev 2022; 27: 393-398.
4. Bartoli CR, Ailawadi G, Kern JA. Diagnosis, nonsurgical management, and prevention of LVAD thrombosis. J Card Surg 2014; 29: 83-94.
5. Cornwell WK 3rd, Ambardekar AV, Tran T, Pal JD, Cava L, Lawley J, et al. Stroke incidence and impact of continuous-flow left ventricular assist devices on cerebrovascular physiology. Stroke 2019; 50: 542-548.
6. Leebeek FWG, Muslem R. Bleeding in critical care associated with left ventricular assist devices: pathophysio­logy, symptoms, and management. Hematology Am Soc Hematol Educ Program 2019; 2019: 88-96.
7. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 2021; 42: 3599-3726.
8. Starling RC, Estep JD, Horstmanshof DA, Milano CA, Stehlik J, Shah KB, et al. Risk assessmentand compara­tive effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: the ROADMAP study 2-year results. JACC Heart Fail 2017; 7: 518-527.
9. Morris AA, Pekarek A, Wittersheim K, Cole RT, Gupta D, Nguyen D, et al. Gender differences in the risk of stroke during support with continuous-flow left ventricular assist device. J Heart Lung Transplant 2015; 34: 1570-1577.
10. Nassif ME, Tibrewala A, Raymer DS, Andruska A, Novak E, Vader JM, et al. Systolic blood pressure on discharge after left ventricular assist device insertion is associated with subsequent stroke. J Heart Lung Transplant 2015; 34: 503-508.
11. Kato TS, Schulze PC, Yang J, Chan E, Shahzad K, Takayama H, et al. Pre-operative and post-operative risk factors associated with neurologic complications in patients with advanced heart failure supported by a left ventricular assist device. J Heart Lung Transplant 2012; 31: 1-8.
12. van den Bergh WM, Lansink-Hartgring AO, van Duijn AL, Engström AE, Lahpor JR, Slooter AJ. Thromboembolic stroke in patients with a HeartMate-II left ventricular assist device – the role of anticoagulation. J Cardiothorac Surg 2015; 10: 128. DOI: 10.1186/s13019-015-0333-7.
13. Kirklin JK, Pagani FD, Kormos RL, Stevenson LW, Blume ED, Myers SL, et al. Eighth annual intermacs report: Special focus on framing the impact of adverse events. J Heart Lung Transplant 2017; 36: 1080-1086.
14. Molina EJ, Shah P, Kiernan MS, Cornwell WK 3rd, Copeland H, Takeda K, et al. The Society of Thoracic Sur­geons Intermacs 2020 annual report. Ann Thorac Surg 2021; 111: 778-792.
15. FDA. Stop New Implants of the Medtronic HVAD System – Letter to Health Care Providers. June 3, 2021.
16. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 2021; 42: 3599-3726.
17. Kiamanesh O, Kaan A, Toma M. Medical management of left ventricular assist device patients: a practical guide for the nonexpert clinician. Can J Cardiol 2020; 36: 205-215.
18. Mehra MR, Netuka I, Uriel N, Katz JN, Pagani FD, Jorde UP, et al.; ARIES-HM3 Investigators. Aspirin and hemocompatibility events with a left ventricular assist device in advanced heart failure: the ARIES-HM3 randomized clinical trial. JAMA 2023; 330: 2171-2181.
19. Bassand JP, Accetta G, Al Mahmeed W, Corbalan R, Eikelboom J, Fitzmaurice DA, et al. Risk factors for death, stroke, and bleeding in 28,628 patients from the GARFIELD-AF registry: rationale for comprehensive management of atrial fibrillation. PLoS One 2018; 13: e0191592. DOI: https://doi. org/10.1371/journal.pone.0191592.
20. Freedman B, Potpara TS, Lip GY. Stroke prevention in atrial fibrillation. Lancet 2016; 388: 806-817.
21. Zimpfer D, Gustafsson F, Potapov E, Pya Y, Schmitto J, Berchtold-Herz M, et al. Two-year outcome after implantation of a full magnetically levitated left ventricular assist device: results from the ELEVATE Registry. Eur Heart J 2020; 41: 3801-3809.
22. Mehra MR, Uriel N, Naka Y, Cleveland JC Jr, Yuzefpolskaya M, Salerno CT, et al. A fully magnetically levitated left ventricular assist device – final report. N Engl J Med 2019; 380: 1618-1627.
23. Berge E, Whiteley W, Audebert H, De Marchis GM, Fonseca AC, Padiglioni C, et al. European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke. Eur Stroke J 2021; 6: I-LXII. DOI: 10.1177/2396987321989865.
24. Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2019; 50: e344-e418. DOI: 10.1161/STR.0000000000000211.
25. Alamowitch S, Turc G, Palaiodimou L, Bivard A, Cameron A, De Marchis GM, et al. European Stroke Organisation (ESO) expedited recommendation on tenecteplase for acute ischaemic stroke. Eur Stroke J 2023; 8: 8-54.
26. Turc G, Tsivgoulis G, Audebert HJ, Boogaarts H, Bhogal P, De Marchis GM, et al. European Stroke Organisation (ESO) – European Society for Minimally Invasive Neurological Therapy (ESMINT) expedited recommendation on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion. J Neurointerv Surg 2022; 14: 209. DOI: 10.1136/neurintsurg-2021-018589.
27. Maïe B, Desilles JP, Mazighi M. Intracranial hemorrhage after reperfusion therapies in acute ischemic stroke patients. Front Neurol 2020; 11: 599908. DOI: 10.3389/fneur.2020.599908.
28. Reda A, Hasanzadeh A, Ghozy S, Sanjari Moghaddam H, Adl Parvar T, Motevaselian M, et al. Risk of symptomatic intracranial hemorrhage after mechanical thrombectomy in randomized clinical trials: a systematic review and meta-analysis. Brain Sci 2025; 15: 63. DOI: 10.3390/brainsci15010063.
29. Al-Mufti F, Bauerschmidt A, Claassen J, Meyers PM, Colombo PC, Willey JZ. Neuroendovascular interventions for acute ischemic strokes in patients supported with left ventricular assist devices: a single-center case series and review of the literature. World Neurosurg 2016; 88: 199-204.
30. Ibech Ch, Mandigo GK, Sisti JA, Lavine SD, Willey JZ. Mechanical thrombectomy after acute ischemic stroke in patients with left ventricular assist devices: a nationwide analysis. Int J Stroke 2023; 18: 215-220.
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). License allowing third parties to download and share its works but not commercially purposes or to create derivative works.
Quick links
© 2025 Termedia Sp. z o.o.
Developed by Bentus.