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3/2007
vol. 109 abstract:
Review paper
The role of chemokines in ocular diseases. Part II. Participation of chemokines in ocular diseases
Roman Malesiński
1
,
Małgorzata Mrugacz
2
,
Alina Bakunowicz-Łazarczyk
2
Klinika Oczna 2007, 109 (3): 345-348
Online publish date: 2007/09/27
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The chemokines are family of ca. 50 chemotactic cytokines produced by leucocytes and tissue cells, which regulate and stimulate leucocytes migration. Dysregulation of this process is apparent in chronic inflammation, allergic eye disease, corneal graft rejection, proliferative vitreoretinopathies and age-related macular degeneration. Antagonists of chemokine receptors have demonstrated anti–inflammatory and antiviral activity and may represent new generations of therapeutic agents.
keywords:
chemokines, chemokine receptors, autoimmune disease |
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POLSKI
