eISSN: 1731-2531
ISSN: 1642-5758
Anaesthesiology Intensive Therapy
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1/2019
vol. 51
 
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abstract:
Review article

Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Jan Pluta
1
,
Janusz Trzebicki
1

1.
I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny
Anestezjologia Intensywna Terapia 2019, tom 51, nr 1, 57–65
Online publish date: 2019/09/12
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Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.
keywords:

haemostasis, thrombocytes; thrombocytopenia; intensive care unit

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