Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Jan Pluta; Janusz Trzebicki

eISSN: 1731-2531
ISSN: 1642-5758

Anaesthesiology Intensive Therapy

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1/2019
vol. 51

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abstract:

Review article

Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Jan Pluta

¹

,

Janusz Trzebicki

¹

I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny

Anestezjologia Intensywna Terapia 2019, tom 51, nr 1, 57–65

Online publish date: 2019/09/12

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Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.

keywords:

Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Jan Pluta 1 , Janusz Trzebicki 1

haemostasis, thrombocytes; thrombocytopenia; intensive care unit

Jan Pluta

¹

,

Janusz Trzebicki

¹