Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery

Hong Jun Yong; Mei Ann Lim; Kenneth Kok; Nadzir Juanda; Sofian Johar

doi:10.5114/amscd.2023.131890

ISSN: 2451-0637

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abstract:

Clinical research

Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery

Hong Jun Yong

¹

,

Mei Ann Lim

¹

,

Kenneth Yuh Yen Kok

¹

,

Nadzir Juanda

²

,

Sofian Johar

²

Pengiran Anak Puteri Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Brunei Darussalam
Gleneagles Jerudong Park Medical Centre, Jerudong Park, Brunei Darussalam

Arch Med Sci Civil Dis 2023; 8: e18–e27

DOI: https://doi.org/10.5114/amscd.2023.131890

Online publish date: 2023/09/30

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AMA

Yong H, Lim M, Kok KY, Juanda N, Johar S. Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery. Archives of Medical Science - Civilization Diseases. 2023;8(1):18-27. doi:10.5114/amscd.2023.131890.

APA

Yong, H., Lim, M., Kok, K. Y., Juanda, N.,  & Johar, S. (2023). Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery. Archives of Medical Science - Civilization Diseases, 8(1), 18-27. https://doi.org/10.5114/amscd.2023.131890

Chicago

Yong, Hong Jun, Mei Ann Lim, Kenneth Y Kok, Nadzir Juanda,  and Sofian Johar. 2023. "Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery". Archives of Medical Science - Civilization Diseases 8 (1): 18-27. doi:10.5114/amscd.2023.131890.

Harvard

Yong, H., Lim, M., Kok, K., Juanda, N.,  and Johar, S. (2023). Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery. Archives of Medical Science - Civilization Diseases, 8(1), pp.18-27. https://doi.org/10.5114/amscd.2023.131890

MLA

Yong, Hong Jun et al. "Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery." Archives of Medical Science - Civilization Diseases, vol. 8, no. 1, 2023, pp. 18-27. doi:10.5114/amscd.2023.131890.

Vancouver

Yong H, Lim M, Kok K, Juanda N, Johar S. Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery. Archives of Medical Science - Civilization Diseases. 2023;8(1):18-27. doi:10.5114/amscd.2023.131890.

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Introduction
Our aims were to characterize the differences in transit time flow measurement (TTFM) between failed and normal grafts, and to determine the association between TTFM and related clinical factors and the likelihood of graft failure and major adverse cardiac events (MACE) following coronary artery bypass grafting.

Material and methods
A retrospective observational analysis was performed on 279 patients admitted between 2017 and 2019, to compare the differences in TTFM between failed and normal grafts, and the association between TTFM and major adverse cardiac events (MACE) – specifically angina, myocardial infarction, and death.

Results
There were no differences in TTFM between failed and normal grafts. There was a greater number of failed grafts with pulsatility index (PI) > 5 compared to PI ≤ 5 (2 = 4.021, p = 0.045). Multivariate analysis showed no significant association between TTFM and MACE. Increased risk of graft failure is associated with the female gender (p = 0.031), history of congestive heart failure (p = 0.025), and poor renal function (p = 0.034). Increased risk of MACE is associated with a history of coronary intervention (p = 0.041), left coronary dominance (p = 0.018), and renal function (p = 0.009).

Conclusions
Patency of graft is influenced by gender, congestive heart failure, and renal function, while MACE is influenced by history of coronary intervention and renal function.

keywords:

Transit time flow measurement as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting surgery

Hong Jun Yong 1 , Mei Ann Lim 1 , Kenneth Yuh Yen Kok 1 , Nadzir Juanda 2 , Sofian Johar 2

transit time flow measurement, graft failure, major adverse cardiac events, coronary artery bypass grafting surgery

Hong Jun Yong

¹

,

Mei Ann Lim

¹

,

Kenneth Yuh Yen Kok

¹

,

Nadzir Juanda

²

,

Sofian Johar

²