Vascular complications in systemic sclerosis

Otylia Kowal-Bielecka

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

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1/2012
vol. 50

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abstract:

Editorial

Vascular complications in systemic sclerosis

Otylia Kowal-Bielecka

Reumatologia 2012; 50, 1: 1–8

Online publish date: 2012/03/02

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Vascular involvement is a permanent feature, and frequently a major clinical problem in patients with systemic sclerosis (scleroderma). Arterial pulmonary hypertension, which develops as a result of proliferative angiopathy of pulmonary arteries, is one of leading causes of mortality in patients with systemic sclerosis. Development of digital ulcers results in significant impairment of health-related quality of life. The progress that has recently been made in the understanding of pathogenesis of scleroderma-related vasculopathy led to the development of new therapies. This article discusses current management of pulmonary hypertension and digital ulcers in patients with systemic sclerosis (Fig. 1, Tables I, II).

keywords:

systemic sclerosis, scleroderma, pulmonary hypertension, digital ulcers

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