eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
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vol. 22
Case report

Ameloblastic fibro-odontoma with chondroid tissue formation

Noura Aly, Hatem Amer, Omar El Khatib

Contemp Oncol (Pozn) 2018; 22 (1): 50-53
Online publish date: 2018/04/03
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Ameloblastic fibro-odontoma (AFO) is an uncommon, benign, mixed odontogenic tumour occurring predominantly in children and adolescents. The purpose of this study was to report an unusual case of AFO in the mandible of a five-year-old male patient showing evidence of chondroid tissue formation. Clinical, radiographic, histopathological and immunohistochemical findings were presented. Intraoral examination revealed a swelling extending from the right deciduous lateral incisor to the left second molar area. Computed tomography (CT) showed a large, well-demarcated multilocular radiolucency with radiopaque deposits. Histologically, the lesion was composed of connective tissue stroma resembling the dental papilla, with epithelial islands, and amorphous masses of enamel and dentin consistent with a diagnosis of AFO, as well as, evidence of large areas showing cartilaginous tissue formation. Immunohistochemistry using cytokeratin, vimentin and s-100 were helpful in determining the origin of the different odontogenic tissues. Surgical excision of the lesion was performed. The patient has been monitored and the lesion has not recurred. We report the first case of AFO showing an unusual behaviour of chondroid tissue formation.

odontogenic tumours, ameloblastic fibro-odontoma, chondroid tissue

El-Naggar KA, Chan KCJ, Grandis RJ, Takata T, Slootweg JP. WHO Classification of Head and Neck Tumours. 4th edition, IARC 2017; 2-17.
Kramer IR, Pindborg JJ, Shear M. Histological typing of odontogenic tumours. Springer Science & Business Media 1992.
Cohen DM, Bhattacharyya I. Ameloblastic fibroma, ameloblastic fibro-odontoma, and odontoma. Oral Maxillofac Surg Clin North Am 2004; 16: 375-84.
Munde AD, Karle RR, Kale UB. Ameloblastic fibroma in one-year-old girl. J Oral Maxillofac Pathol 2013; 17: 149.
Cahn LR, Blum T. Ameloblastic odontoma: case report critically analyzed. J Oral Surg 1952; 10: 169-70
Slootweg PJ. An analysis of the interrelationship of the mixed odontogenic tumours – ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas. Oral Surg Oral Med Oral Pathol 1981; 51: 266-76.
Gardner DG. The mixed odontogenic tumours. Oral Surg Oral Med Oral Pathol. 1984; 58: 166-8.
Sreenath G, Reddy I, Sreenivasreddy P. Ameloblastic fibro-odontome (AFO) of the mandible: A case report. J Clin Diagn Res 2014; 8: 260-2.
Nelson BL, Thompson LD. Ameloblastic fibro-odontoma. Head Neck Pathol 2014; 8: 168-70.
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