Menopause Review
eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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4/2025
vol. 24
 
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Original paper

Association of C-reactive protein-triglyceride-glucose index with all-cause and cardiovascular mortality in postmenopausal women

Jindong Wang
1
,
Aijin Li
2
,
Yaping Wang
2
,
Yanyun Liu
2

  1. Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China
  2. Department of Obstetrics and Gynecology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou,Zhejiang, China
Menopause Rev 2025; 24(4): 259-267
Online publish date: 2026/02/04
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1. Kamińska MS, Schneider-Matyka D, Rachubińska K, Panczyk M, Grochans E, Cybulska AM. Menopause predisposes women to increased risk of cardiovascular disease. J. Clin Med 2023; 12: 7058.
2. Tang N, Chen X, Li H, Cheng S, Hu Y, Wang L, et al. Association of C-reactive protein triglyceride glucose index with mortality in coronary heart disease and type 2 diabetes from NHANES data. Sci Rep 2025; 15: 24687.
3. Ou H, Wei M, Li X, Xia X. C-reactive protein-triglyceride glucose index in evaluating cardiovascular disease and all-cause mortality incidence among individuals across stages 0–3 of cardiovascular-kidney-metabolic syndrome: a nationwide prospective cohort study. Cardiovasc Diabetol 2025; 24: 296.
4. Hartley A, Rostamian S, Kaura A, Chrysostomou P, Welsh P, Ariti C, et al. The relationship of baseline high-sensitivity C-reactive protein with incident cardiovascular events and all-cause mortality over 20 years. EBioMedicine 2025: 105786.
5. Di Rosa M, Sabbatinelli J, Giuliani A, Carella M, Magro D, Biscetti L, et al. Correction: Inflammation scores based on C‑reactive protein and albumin predict mortality in hospitalized older patients independent of the admission diagnosis. Immun Ageing 2024; 21: 79.
6. Shan Y, Liu Q, Gao T. Application of the C-reactive protein-triglyceride glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study. BMC Endocr Disord 2025; 25: 126.
7. XuY, Chen S, Zhu J, Wang Q, Li W, Pan G. C-reactive protein-triglyceride glucose index and stroke risk in early cardiovascular-kidney-metabolic syndrome: a National cohort study. BMC Cardiovasc Disord 2025; 25: 634.
8. Zhao DF. Value of C-reactive protein-triglyceride glucose index in predicting cancer mortality in the general population: results from National health and nutrition examination survey. Nutr Cancer 2023; 75: 1934-1944.
9. Sun Y, Guo Y, Ma S, Mao Z, Meng D, Xuan K,et al. Association of C-reactive protein-triglyceride glucose index with the incidence and mortality of cardiovascular disease: a retrospective cohort study. Cardiovasc Diabetol 2025; 24: 313.
10. Tang S, Wang H, Li K, Chen Y, Zheng Q, Meng J, et al. 2024. C-reactive protein-triglyceride glucose index predicts stroke incidence in a hypertensive population: a national cohort study. Diabetol Metab Syndr 2024; 16: 277.
11. Tang Y, Peng B, Liu J, Liu Z, Xia Y, Geng B. Systemic immune-inflammation index and bone mineral density in postmenopausal women: a cross-sectional study of the national health and nutrition examination survey (NHANES) 2007–2018. Front Immunol 2022; 13: 975400.
12. Zhang B, Jiang D, Ma H, Liu H. Association between triglyceride-glucose index and its obesity indicators with hypertension in postmenopausal women: a cross-sectional study. Front Nutr 2025; 12: 1623697.
13. Von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbrouc-ke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med 2007; 335: e296.
14. Vandenbroucke JP, von Elm E, Altman DG, Gøtzsche PC, Mulrow CD, Pocock SJ, et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. PLoS Med 2007; 12: e297.
15. Ruan GT, Xie HL, Zhang HY, Liu CA, Ge YZ, Zhang Q, et al. A novel inflammation and insulin resistance related indicator to predict the survival of patients with cancer. Front Endocrinol 2022; 13: 905266.
16. Eisenhardt SU, Habersberger J, Peter K. Monomeric C-reactive protein generation on activated platelets: the missing link between inflammation and atherothrombotic risk. Trends Cardiovasc Med 2009; 19: 232-237.
17. Cuesta-López L, Arias-de la Rosa I, Martín-Salazar JE, Barranco AM, Ladehesa-Pineda L, Ruiz-Ponce M, et al. Molecular insights into the relationship between sustained CRP elevation and endothelial dysfunction in axial spondyloarthritis. RMD Open 2025; 11: e005746.
18. Kahraman E, Cetin S, Cetin M, Ulgen A. Two sides of the coin: coagulation and inflammation in deep vein thrombosis – a prospective study on D-dimer and SIRI. Front Med 2025; 12: 1604286.
19. Lizcano F, Guzmán G. Estrogen deficiency and the origin of obesity during menopause. Biomed Res Int 2014; 2014: 757461.
20. Zhang L, Qiu N, Chen X, Luo T, Zhang M, Yang J, et al. Insulin resistance in school-age children: comparison surrogate diagnostic markers. Pediatr Res 2025.
21. Karadeniz Y, Burgucu H, Caliskan Y, Ozturk Z, Yarar H, Kaynak M, et al. Comparison of triglyceride-glucose index and HOMA-IR in assessing insulin resistance in acromegaly: a case-control study. Endokrynol Pol 2025; 76: 442-449.
22. Zhou H, Shi Y, Zhou X. Comparison of nine insulin resistance surrogates for predicting cardiovascular disease: a cohort study. Diabetol Metab Syndr 2025; 17: 365.
23. Pan Y, Du B, Feng L, Bi J. Comparative analysis of 16 baseline obesity and lipid-related indices for cardiovascular disease risk prediction in adults with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide prospective cohort study. Diabetol Metab Syndr 2025; 17: 343.
24. Fritz J, Bjørge T, Nagel G, Manjer J, Engeland A, Häggström C, et al. The triglyceride-glucose index as a measure of insulin resistance and risk of obesity-related cancers. Int J Epidemiol 2020; 49: 193-204.
25. Shi H, Zhou L, Yang S, Zhou H. The relationship between triglyceride and glycose (TyG) index and the risk of gynaecologic and breast cancers. Clin Nutr ESPEN 2022; 51: 345-352.
26. Lai T, Guan F, Chen Y, Hu K. Cross-sectional comparison of the association between three different insulin resistance surrogates and frailty: NHANES 1999–2018. Front Endocrinol 2024; 15: 1439326.
27. Yin H, Guo L, Zhu W, Li W, Zhou Y, Wei W, et al. Association of the triglyceride-glucose index and its related parameters with frailty. Lipids Health Dis 2024; 23: 150.
28. Long Q, Li Y, Shi Z, Lee Y, Mao L. Investigation of the association between the triglyceride-glucose index and the incidence of frailty among middle-aged and older adults: evidence from the China health and retirement longitudinal study. Front Public Health 2025; 13: 1548222.
29. Yang T, Li G, Wang C, Xu G, Li Q, Yang Y, et al. Insulin resistance and coronary inflammation in patients with coronary artery disease: a cross-sectional study. Cardiovasc Diabetol 2024; 23: 79.
30. Jin A, Wang S, Li J, Wang M, Lin J, Li H, et al. Mediation of systemic inflammation on insulin resistance and prognosis of nondiabetic patients with ischemic stroke. Stroke 2023; 54: 759-769.
31. Ali AM, Mousa NMA, Elgendy SKM, Al-Emrany AM, Saber OSA, Elhakk SMA, et al. Effect of lifestyle changes on liver enzymes, triglycerides, sex hormones, and daytime sleepiness in polycystic ovarian syndrome women with obstructive sleep apnea and fatty liver – a randomized controlled trial. Prz Menopauz 2025; 24: 94-101.
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