Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years

Oliver Robles-Guardamino; Jesse M. Sánchez-Vargas; Karla M. Joo; Ericson Gutierrez; Hellen L. La Torre; José F. Parodi; Fernando M. Runzer-Colmenares

doi:10.5114/pm.2025.154677

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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3/2025
vol. 24

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abstract:

Original paper

Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years

Oliver Robles-Guardamino

¹

,

Jesse M. Sánchez-Vargas

²

,

Karla M. Joo

³

,

Ericson Gutierrez

⁴

,

Hellen L. La Torre

³

,

José F. Parodi

³

,

Fernando M. Runzer-Colmenares

¹

Carrera de Medicina Humana, CHANGE Research Working Group, Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru
Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Peru
Facultad de Medicina Humana, Centro de Investigación del Envejecimiento (CIEN), Universidad San Martín de Porres, Lima, Peru
Universidad San Ignacio de Loyola, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Lima, Peru

Menopause Rev 2025; 24(3): 149-155

DOI: https://doi.org/10.5114/pm.2025.154677

Online publish date: 2025/10/04

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AMA

Robles-Guardamino O, Sánchez-Vargas J, Joo K, et al. Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years. Menopause Review/Przegląd Menopauzalny. 2025;24(3):149-155. doi:10.5114/pm.2025.154677.

APA

Robles-Guardamino, O., Sánchez-Vargas, J., Joo, K., Gutierrez, E., Torre, H.,  & Parodi, J. et al. (2025). Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years. Menopause Review/Przegląd Menopauzalny, 24(3), 149-155. https://doi.org/10.5114/pm.2025.154677

Chicago

Robles-Guardamino, Oliver, Jesse M. Sánchez-Vargas, Karla M. Joo, Ericson Gutierrez, Hellen L. La Torre, José F. Parodi,  and Fernando M. Runzer-Colmenares. 2025. "Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years". Menopause Review/Przegląd Menopauzalny 24 (3): 149-155. doi:10.5114/pm.2025.154677.

Harvard

Robles-Guardamino, O., Sánchez-Vargas, J., Joo, K., Gutierrez, E., Torre, H., Parodi, J.,  and Runzer-Colmenares, F. (2025). Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years. Menopause Review/Przegląd Menopauzalny, 24(3), pp.149-155. https://doi.org/10.5114/pm.2025.154677

MLA

Robles-Guardamino, Oliver et al. "Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years." Menopause Review/Przegląd Menopauzalny, vol. 24, no. 3, 2025, pp. 149-155. doi:10.5114/pm.2025.154677.

Vancouver

Robles-Guardamino O, Sánchez-Vargas J, Joo K, Gutierrez E, Torre H, Parodi J et al. Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years. Menopause Review/Przegląd Menopauzalny. 2025;24(3):149-155. doi:10.5114/pm.2025.154677.

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Introduction
To determine whether the need for hospitalization is more frequent in patients with both frailty and functional dependence compared to patients with only frailty or functional dependence. We also performed an analysis stratified by sex.

Material and methods
An observational, analytical, retrospective cohort study that analyzed a secondary database of a study including a population of 1896 older adults cared for by the Geriatric Service of the “Naval Medical Center” of Peru from 2010 to 2015. The analysis of the data was done using the program STATA version 15.0.

Results
There was a statistically significant association between age (p = 0.001), education (p = 0.003), number of comorbidities (p = 0.01), frailty (p = 0.001), coexistence between frailty and functional dependence (p = 0.001) and the number of hospitalizations. The mean number of hospitalization days was greater among the older adults with both frailty and functional dependence compared to those who were only frail or functionally dependent (2.6 ±1.6 vs. 2.3 ±1.5 vs. 0.7 ±0.7; p = 0.001, respectively). This association was maintained in women and men.

Conclusions
The coexistence of functional dependence and frailty is associated with a greater number of hospitalizations in older male and female adults. This is relevant because frailty can be avoided by implementing promotional and preventive interventions of active aging and at the same time, it is potentially reversible with an early detection and adequate measures such as physical activity, diet, and cognitive training.

keywords:

Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years

Oliver Robles-Guardamino 1 , Jesse M. Sánchez-Vargas 2 , Karla M. Joo 3 , Ericson Gutierrez 4 , Hellen L. La Torre 3 , José F. Parodi 3 , Fernando M. Runzer-Colmenares 1

functional dependence, frailty, hospitalization, elderly

Oliver Robles-Guardamino

¹

,

Jesse M. Sánchez-Vargas

²

,

Karla M. Joo

³

,

Ericson Gutierrez

⁴

,

Hellen L. La Torre

³

,

José F. Parodi

³

,

Fernando M. Runzer-Colmenares

¹