Menopause Review
eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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3/2025
vol. 24
 
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abstract:
Original paper

Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years

Oliver Robles-Guardamino
1
,
Jesse M. Sánchez-Vargas
2
,
Karla M. Joo
3
,
Ericson Gutierrez
4
,
Hellen L. La Torre
3
,
José F. Parodi
3
,
Fernando M. Runzer-Colmenares
1

  1. Carrera de Medicina Humana, CHANGE Research Working Group, Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru
  2. Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Peru
  3. Facultad de Medicina Humana, Centro de Investigación del Envejecimiento (CIEN), Universidad San Martín de Porres, Lima, Peru
  4. Universidad San Ignacio de Loyola, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Lima, Peru
Menopause Rev 2025; 24(3): 149-155
DOI: https://doi.org/10.5114/pm.2025.154677
Online publish date: 2025/10/04
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Introduction
To determine whether the need for hospitalization is more frequent in patients with both frailty and functional dependence compared to patients with only frailty or functional dependence. We also performed an analysis stratified by sex.

Material and methods
An observational, analytical, retrospective cohort study that analyzed a secondary database of a study including a population of 1896 older adults cared for by the Geriatric Service of the “Naval Medical Center” of Peru from 2010 to 2015. The analysis of the data was done using the program STATA ver­sion 15.0.

Results
There was a statistically significant association between age (p = 0.001), education (p = 0.003), number of comorbidities (p = 0.01), frailty (p = 0.001), coexistence between frailty and functional dependence (p = 0.001) and the number of hospitalizations. The mean number of hospitalization days was greater among the older adults with both frailty and functional dependence compared to those who were only frail or function­ally dependent (2.6 ±1.6 vs. 2.3 ±1.5 vs. 0.7 ±0.7; p = 0.001, respectively). This association was maintained in women and men.

Conclusions
The coexistence of functional dependence and frailty is associated with a greater number of hospitalizations in older male and female adults. This is relevant because frailty can be avoided by implement­ing promotional and preventive interventions of active aging and at the same time, it is potentially reversible with an early detection and adequate measures such as physical activity, diet, and cognitive training.

keywords:

functional dependence, frailty, hospitalization, elderly
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