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Reumatologia/Rheumatology
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Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
3/2008
vol. 46
 
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abstract:

CASE REPORT
Adenocarcinoma of the colon in a patient with systemic sclerosis

Małgorzata Widuchowska
,
Magdalena Kopeć-Mędrek
,
Eugeniusz J. Kucharz

Reumatologia 2008; 46, 3: 168–171
Online publish date: 2008/07/09
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Systemic sclerosis is a chronic connective tissue disorder characterised by progressive fibrosis of the skin and subcutaneous tissue, occurrence of Raynaud’s phenomenon and other vascular abnormalities as well as internal organ involvement due to fibrosis, especially within the alimentary tract, lungs, heart and kidneys. Malignant tumours are also found in the patients but it remains unclear whether the disease is associated with higher incidence of malignancy. Some authors provide evidence of an increased incidence of cancer in patients with scleroderma, while others do not confirm this correlation. Most of the studies report a statistically significant relation of systemic sclerosis to increased risk of lung cancer. The paper reviews a patient suffering from systemic sclerosis for a few years with recent diagnosis of adenocarcinoma of the colon.
keywords:

systemic sclerosis, adenocarcinoma of the colon, risk of cancer
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