Abstract
Comparative effect of aerobic training vs resistance exercise on homocysteine levels and cardiovascular risk factors in type 2 diabetic individuals: a randomized clinical trial
- Department of Physical Therapy for Cardiopulmonary/Geriatric Disorders, Faculty of Physical Therapy, Egyptian Chinese University, Cairo, Egypt
- Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Background
Elevated plasma homocysteine level is closely associated with an increased risk of developing peripheral vascular disease, atherothrombotic coronary artery disease, myocardial infarction, and stroke. Thus, it is considered an important cardiovascular risk factor.
Objectives
This study was designed to look into the results of both aerobic and anaerobic exercises on homocysteine and cardiovascular risk factors (insulin, cholesterol, and aerobic capacity) in people with type 2 diabetes and to compare them.
Material and methods
A randomized clinical experiment with a prospective design. It was conducted at El-Sherouk Public Hospital, Physical Therapy Department. 40 males with type 2 diabetes mellitus were randomly divided into two groups. Aerobic activities were performed by group (A), whereas resistance training was performed by group (B). Patients’ blood homocysteine, insulin, and cholesterol levels and ability to complete a 6-minute walk test were assessed at the start of the intervention and twelve weeks post-intervention.
Results
All outcome indicators improved significantly, favoring Group (A) over Group (B) (p = 0.001).
Conclusions
Aerobic exercises have a higher effect than resistance exercises in lowering homocysteine cardiovascular risk factors (insulin and cholesterol and improving aerobic fitness) in type 2 diabetic patients.
Keywords
type 2 diabetes mellitus, homocysteine, cholesterol, insulin, exercise
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