Prenatal Cardiology

Abstract

1/2020
Case report

Concomitant effects of late fetal growth restriction and intra-cytoplasmatic sperm injection on fetal cardiac remodelling: a case report

  1. Division of Maternal Fetal Medicine Ospedale Cristo Re Roma, Università di Roma Tor Vergata, Roma, Italy
  2. Department of Obstetrics and Gynaecology, The First I.M. Sechenov Moscow State Medical University, Moscow, Russia
Prenat Cardio 2020; 10(1); 65-68
Online publish date: 2020/12/29
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Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
Fetuses conceived by intra-cytoplasmatic sperm injection (ICSI) and complicated by fetal growth restriction (FGR) are characterised by a different phenotype of cardiac remodelling. We present a case in which both conditions, ICSI and late FGR, were present. An echocardiographic study of the fetal cardiac geometry showed the presence of a globular heart with sphericity indices of both ventricles values < 5th centile, not associated with dilated heart, as present in ICSI fetuses. The possible pathophysiological changes of these findings are discussed.
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