eISSN: 2449-6731
ISSN: 2449-6723
Prenatal Cardiology
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Case report

Concomitant effects of late fetal growth restriction and intra-cytoplasmatic sperm injection on fetal cardiac remodelling: a case report

Ilenia Mappa
Maria Luviso
Pavjola Maqina
Giuseppe Rizzo
1, 2

  1. Division of Maternal Fetal Medicine Ospedale Cristo Re Roma, Università di Roma Tor Vergata, Roma, Italy
  2. Department of Obstetrics and Gynaecology, The First I.M. Sechenov Moscow State Medical University, Moscow, Russia
Prenat Cardio 2020; 10(1); 65-68
Online publish date: 2020/12/29
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Fetuses conceived by intra-cytoplasmatic sperm injection (ICSI) and complicated by fetal growth restriction (FGR) are characterised by a different phenotype of cardiac remodelling. We present a case in which both conditions, ICSI and late FGR, were present. An echocardiographic study of the fetal cardiac geometry showed the presence of a globular heart with sphericity indices of both ventricles values < 5th centile, not associated with dilated heart, as present in ICSI fetuses. The possible pathophysiological changes of these findings are discussed.

intra-cytoplasmatic sperm injection, fetal growth restriction, fetal cardiac geometry, fetal cardiac remodelling, echocardiography, sphericity index

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