Diagnosis and therapy of crystal-induced diseases

Irena Zimmermann-Górska

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Subscription Contact Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

2/2012
vol. 50

Send email

Copy url:

abstract:

Short communication

Diagnosis and therapy of crystal-induced diseases

Irena Zimmermann-Górska

Reumatologia 2012; 50, 2: 177–180

Online publish date: 2012/06/01

View full text Get citation

Clinical symptoms as well as the classification criteria of gout are presented. Identification of monosodium urate monohydrate crystals in synovial fluid or tophus aspirates permits a definite diagnosis of gout. Oral colchicine and/or non‑steroidal anti-inflammatory drugs (NSAIDs) are first line agents for treatment of acute attacks. The therapeutic goal of urate lowering therapy is maintaining the serum uric acid ≤ 6 mg/dl (375 μmol/l).

Definite diagnosis of calcium pyrophosphate deposition (CPPD) is by identification of calcium pyrophosphate crystals in synovial fluid or biopsied tissue. Radiographic chondrocalcinosis supports the diagnosis. For acute calcium pyrophosphate crystal arthritis, joint aspiration combined with steroid injection is often sufficient. Oral colchicine and/or (NSAIDs) are an effective alternative.

keywords:

gout, uric acid, calcium pyrophosphate

EVENTS/KONFERENCJE

BOOKS/KSIĄŻKI