eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
Current issue Archive Manuscripts accepted About the journal Special Issues Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank


 
4/2018
vol. 17
 
Share:
Share:
more
 
 
abstract:
Original paper

Diagnostic value of histopathological examination results obtained during screening of patients with diagnosed atypical hyperplasia

Jakub Malinowski, Miłosz Wilczyński, Adam Depta, Andrzej Malinowski

Menopause Rev 2018; 17(4): 144-148
Online publish date: 2018/12/31
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Vulvovaginal atrophy accompanied by lower urinary tract dysfunction related to low levels of estrogen and androgens is labeled as genitourinary syndrome of menopause (GSM). Although this condition affects most postmenopausal women worldwide, it seems to be underdiagnosed and undertreated. Women should be properly advised to choose an adequate treatment modality to improve their quality of life, sexual relationships and social activity. The aim of this article is to increase knowledge of GSM. The current treatment options, both hormonal and non-hormonal, are reviewed. Topical estrogen therapy still remains the gold standard, but the demand for individually tailored therapy is growing. New treatment modalities are continuously included in clinical practice. They should consider the whole personality of a woman as well as cultural and social factors. Further studies on GSM and on the effectiveness of various treatment options are necessary to achieve this purpose.
keywords:

endometrial hyperplasia, atypical hyperplasia, endometrioid intraepithelial neoplasia, endometrial cancer

references:
Chen Y-L, Cheng W-F, Lin M-C, et al. Concurrent Endometrial Carcinoma in Patients with a Curettage Diagnosis of Endometrial Hyperplasia. J Formos Med Assoc 2009; 108: 502-507.
Mutter GL. Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos? The Endometrial Collaborative Group. Gynecol Oncol 2000; 76: 287-290.
Sobczuk K, Sobczuk A. New classification system of endometrial hyperplasia WHO 2014 and its clinical implications. Menopause Rev 2017; 16: 107-111.
Montgomery BE, Daum GS, Dunton CJ. Endometrial hyperplasia: a review. Obstet Gynecol Surv 2004; 59: 368-378.
Gawron I, Łoboda M, Babczyk D, et al. Endometrial cancer and hyperplasia rate in women before menopause with abnormal uterine bleeding undergoing endometrial sampling. Przegl Lek 2017; 74: 139-143.
Practice Bulletin No. 149: Endometrial cancer. Obstet Gynecol 2015; 125: 1006-1026.
WHO Classification of Tumours of Female Reproductive Organs. Kurman RJ, Carcangiu ML, Herrington CS, Young RH (eds.). 4th ed. International Agency for Research on Cancer (IARC). Lyon 2014; 121-154.
Bobin L, Malinowski A. Rozrosty endometrium – diagnostyka i leczenie. Menopause Rev 2007; 4: 212-219.
Trimble CL, Kauderer J, Zaino R. Concurrent Endometrial Carcinoma in Women with a Biopsy Diagnosis of Atypical Endometrial Hyperplasia. Cancer 2006; 106: 812-819.
Sajdak S, Markowska A, Rehlis S, Ludwin I. Histeroskopia w leczeniu oszczędzającym płodność w przypadkach rozrostów atypowych i wczesnego raka endometrium – korzyści i zagrożenia. Curr Gynecol Oncol 2016; 14: 231-236.
Colombo N, Creutzberg C, Amant F, et al. ESMO-ESGO-ESTRO Endometrial Consensus Conference Working Group: ESMO-ESGO-ESTRO Consensus Conference on Endometrial Cancer: diagnosis, treatment and follow-up. Ann Oncol 2016; 27: 16-41.
de Rijk SR, Steenbergen ME, Nieboer TE, Coppus SF. Atypical Endometrial Polyps and Concurrent Endometrial Cancer. Obstet Gynecol 2016; 128: 519-525.
Lacey JV, Sherman ME, Rush BB, et al. Absolute Risk of Endometrial Carcinoma During 20-Year Follow-Up Among Women With Endometrial Hyperplasia. J Clin Oncol 2010; 28: 788-792.
Nieminen TT, Gylling A, Abdel-Rahman WM, et al. Molecular Analysis of Endometrial Tumorigenesis: Importance of Complex Hyperplasia Regardless of Atypia. Clin Cancer Res 2009; 15: 5772-5783.
Sznurkowski JJ, Knapp P, Bodnar L, et al. Zalecenia Polskiego Towarzystwa Ginekologii Onkologicznej dotyczące diagnostyki i leczenia raka endometrium. Curr Gynecol Oncol 2017; 15: 34-44.
Management of endometrial hyperplasia. Royal College of Obstetricians and Gynaecologists/British Society for Gynaecological Endoscopy Green-top Guideline No. 67. RCOG/BSGE Joint Guideline, February 2016.
Zhang C, Wang EY, Liu F, et al. Routine histologic features in complex atypical hyperplasia can predict the presence of endometrial carcinoma: a clinicopathological study of 222 cases. Hum Pathol 2018; 80: 40-46.
Spaczyński M. Nowotwory trzonu macicy. In: Położnictwo i ginekologia, Bręborowicz GH (ed.). PZWL, Warszawa 2010; 833-842.
Cramer DW. The Epidemiology of Endometrial and Ovarian Cancer. Hematol Oncol Clin North Am 2012; 26: 1-12.
Mittal K, Da Costa D. Endometrial Hyperplasia and Carcinoma in Endometrial Polyps: Clinicopathologic and Follow-Up Findings. Int J Gynecol Pathol 2008; 27: 45-48.
Zhang C, Sung J, Quddus MR. Association of ovarian hyperthecosis with endometrial polyp, endometrial hyperplasia, and endometrioid adenocarcinoma in postmenopausal women: a clinicopathological study of 238 cases. Hum Pathol 2017; 59: 120-124.
Kurman RJ, Kaminski PF, Norris HJ. The behawior of endometrial hyperplasia: A long-term study of untreated hyperplasia in 170 patients. Cancer 1985; 56: 403-412.
Chen YL, Cheng W-F, Lin M-C. Concurrent Endometrial Carcinoma in patients with a Curettage Diagnosis of Endometrial Hyperplasia. Formos Med Assoc 2009; 108: 502-507.
Montgomery BE, Daum GS, Dunton CJ. Endometrial hyperplasia: a review. Obstet Gynecol Surv 2004; 59: 368-78.
Merisio C, Berretta R, De Ioris A, et al. Endometrial cancer in patients with preoperative diagnosis of atypical endometrial hyperplasia. Eur J Obstet Gynecol Reprod Biol 2005; 122: 107-111.
Cwonda Ł, Wójcik-Krowiranda K, Michalski T, et al. Analiza wyników badań histopatologicznych materiału przed- i pooperacyjnego w nabłonkowych nowotworach złośliwych błony śluzowej trzonu macicy. Curr Gynecol Oncol 2017; 15: 105-112.
NCCN Clinical Practice Guidelines in Oncology (NCCN Guide­lines): Uterine neoplasms. Version 1.2017 – November 21, 2016. Available from: https://www.nccn.org/professionals/physician_ gls/pdf/uterine.pdf.
Bourdel N, Chauvet P, Tognazza E, et al. Sampling in atypical endometrial hyperplasia: which method results in the lowest underestimation of endometrial cancer? A systematic review and meta-analysis. J Minim Invasive Gynecol 2016; 23: 692-701.
Ludwin A, Pityński K, Szczudrawa A, et al. [Value of saline infu­sion sonohysterography and hysteroscopy in postmenopausal patient with persistent abnormal ultrasonographic images after endometrial curettage with normal histological results]. Ginekol Pol 2003; 74: 786-792.
Spiewankiewicz B, Stelmachów J, Sawicki W, et al. The effective­ness of hysteroscopic polypectomy in cases of female infertility. Clin Exp Obstet Gynecol 2003; 30: 23-25.
Ceci O, Bettocchi S, Pellegrino A, et al. Comparison of hysteroscopic and hysterectomy findings for assessing the diagnostic accuracy of off ice hysteroscopy. Fertil Steril 2002; 78: 628-631.
Epstein E, Ramirez A, Skoog L, et al. Dilatation and curettage fails to detect most focal lesions in the uterine cavity in women with postmenopausal bleeding. Acta Obstet Gynecol Scand 2001; 80: 1131-1136.
Mitchard J, Hirschowitz L. Concordance of FIGO grade of endometrial adenocarcinomas in biopsy and hysterectomy specimens. Histo- pathology 2003; 42: 372-378.
FEATURED PRODUCTS
Quick links
© 2019 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe