Abstract
Double protection in patients with a massive thrombus in the infarct-related artery – a single-center retrospective study
- Silesian Center for Heart Diseases, Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Medical University of Silesia, Zabrze, Poland
- Silesian Center for Heart Diseases, 3rd Department of Cardiology, Medical University of Silesia, Zabrze, Poland
- Doctoral School, Division of Medical Sciences in Zabrze, Medical University of Silesia, Department of Cardiology, Silesian Center for Heart Diseases, Zabrze, Poland
Introduction:
ST-segment elevation myocardial infarction (STEMI) is associated with thrombus formation on a ruptured or ulcerated atherosclerotic plaque. The consequences of a massive thrombus (MT) may include lack of reperfusion, extensive myocardial infarction (MI) and its complications. Although there are various treatment options for patients with coronary thrombi, double protection (DP) – manual thrombectomy (MTH) with a distal protection device (DPD) – has not been tested yet.
Aim:
To present DP outcomes in the treatment of patients with STEMI and MT patients.
Material and methods:
Fourteen patients with STEMI and MT were included in the study. Those patients underwent primary percutaneous coronary intervention (PPCI) with DP.
Results:
Inferior MI was found in 12 (85.8%) patients. Stents were implanted in 13 (92.8%) patients. Thrombolysis In Myocardial Infarction (TIMI) Thrombus Grade 5 was present in 11 (78.6%) patients and Grade 4 in 3 (21.4%) patients. The median thrombus length was 39.1 mm. Complete reperfusion (TIMI flow 3) was observed in 11 (78.6%) patients and TIMI flow 2 in 3 (21.4%) patients. Myocardial Blush Grade (MBG) was used in patients with TIMI flow 3 and Grade 3 was found in 5 (35.7%) patients. Resolution in ST-segment elevation > 50% was obtained in 13 (92.8%) patients. No myocardial rupture, stroke, or death occurred during hospitalization.
Conclusions:
DP in MT patients is a safe and feasible procedure. However, further observations and studies are needed to assess the efficacy of this method.
Keywords
ST-segment elevation myocardial infarction, primary percutaneous coronary intervention, manual thrombectomy, distal protection device, massive thrombus
Integrated with