Advances in Interventional Cardiology
eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
Current Issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
1/2026
vol. 22
 
Share:
Send email
Share:
abstract:
Original paper

Female sex as a possible factor associated with favorable long-term outcomes in off-pump coronary artery bypass surgery

Tomasz K. Urbanowicz
1
,
Michał Michalak
2
,
Antoni F. Araszkiewicz
3
,
Paweł Wójcik
3
,
Krzysztof Jańczak
4
,
Szymon Kubiak
3
,
Marek Jemielity
1

  1. Cardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland
  2. Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland
  3. Poznan University of Medical Sciences, Cardiac Surgery Students Research Group, Poznan, Poland
  4. Poznan University of Medical Sciences, Cardiology Students Research Group, Poznan, Poland
Adv Interv Cardiol 2026; 22, 1 (83): 97–102
DOI: https://doi.org/10.5114/aic.2026.160035
Online publish date: 2026/03/09
View full text Get citation
 
Introduction
Surgical revascularization, alongside percutaneous intervention, is a viable therapeutic option with satisfactory long-term results. Accumulating evidence indicates that biological sex modulates the predisposition to coronary artery disease and perioperative risk.

Aim
The study aimed to identify potential long-term prognostic factors after surgical revascularization in patients undergoing off-pump coronary artery bypass (OPCAB) using bilateral mammary arteries.

Material and methods
In total, 276 consecutive patients were operated on due to complex stable coronary disease with off-pump surgical revascularization using bilateral mammary arteries. The long-term survival rates, including the Kaplan-Meier survival curve, were compared based on all-cause mortality risk between the female and male populations.

Results
Among the 276 analyzed participants, 64 (23%) were deceased, with a median follow-up time of 3,307 days (range: 1,703–5,414 days). The 5-, 10-, and 15-year survival rates in the male and female populations were 90.5% vs. 96.5%, 78.1% vs. 91.4%, and 62.9% vs. 81.3%, respectively.

Conclusions
Female sex may be related to superior long-term survival in off-pump revascularization with bilateral mammary artery grafts. While early perioperative risks may be higher in women due to anatomical and referral delay factors, the long-term survival in women may surpass that of men once the immediate postoperative period is successfully navigated. Large-scale studies are required to confirm the suggested association.

keywords:

females, revascularization, off-pump coronary artery bypass, off-pump, sex differences

Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2026 Termedia Sp. z o.o.
Developed by Termedia.