eISSN: 2084-9885
ISSN: 1896-6764
Neuropsychiatria i Neuropsychologia/Neuropsychiatry and Neuropsychology
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1-2/2021
vol. 16
 
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abstract:
Review paper

Functional resonance as a tool to support diagnosis of schizophrenic patients

Ilona Sylwia Karpiel
1
,
Zofia Kurasz
2

1.
Sieć Badawcza Łukasiewicz – Instytut Techniki i Aparatury Medycznej w Zabrzu
2.
Szkoła Doktorska, Uniwersytet Śląski w Katowicach
Neuropsychiatria i Neuropsychologia 2021; 16, 1–2: 52–60
Online publish date: 2021/07/27
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Functional magnetic resonance imaging (fMRI) is a technique for measuring brain activity, which is based on measurement of the signal generated by the difference between oxyhemoglobin and oxygen-depleted blood. With fMRI there has been a clear increase in interest in a specialized method of resting state functional magnetic resonance imaging (rsfMRI). RsfMRI is one of the few methods that extend the diagnosis of the human brain allowing for taskless visualization of neural network connections underlying the behavioral deficits manifested in schizophrenia. Schizophrenia is a serious mental disorder characterized by episodes of disease with positive symptoms such as delusions and hallucinations, negative symptoms such as apathy or lack of drive, and cognitive disorders that have a huge impact on the global functioning of the patient. In recent years there has been a significant increase in the number of studies showing the use of both fMRI and rsfMRI in neurobiological studies. This article summarizes the features of the fMRI and rsfMRI methodology, and emphasizes their application in neurobehavioral studies focusing on schizophrenia. After more than 100 years of research, there is no universally accepted theory of neuropathology of schizophrenia; it still remains an unexplained disease. Is a debilitating and often disabling brain disorder, characterized by a heterogeneous presentation of psychological and behavioral dysfunctions. Screening of cognitive functions in schizophrenia can help to assess the functioning of the central nervous system and observe changes caused by the disease and the impact of treatment on the course of the disease.
keywords:

fMRI, schizophrenia, neuroimaging, brain

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