en POLSKI
eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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6/2011
vol. 49
 
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abstract:
Case report

HELLP syndrome in a patient with systemic lupus erythematosus and secondary antiphospholipid syndrome

Joanna Kur-Zalewska
,
Danuta Choroś
,
Olga Bujakowska
,
Romuald Dębski
,
Witold Tłustochowicz

Reumatologia 2011; 49, 6: 456–458
Online publish date: 2011/12/28
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The presence of connective tissue diseases is associated with numerous pregnancy complications, such as recurrent miscarriages, intrauterine growth retardation or preeclampsia. A case of a 36-year-old woman with systemic lupus erythematosus and secondary antiphospholipid syndrome who developed a syndrome of haemolysis, elevated liver enzymes and low platelet count (HELLP syndrome) at 17 weeks of gestation is described. Treatment with corticosteroids, subcutaneous heparin, intravenous immunoglobulin and hypotensive drugs led to improvement of the clinical symptoms and normalization of laboratory parameters. Despite treatment, intrauterine foetal death occurred at 18 weeks of gestation. The purpose of this case report is to increase awareness of the possibility of early onset of HELLP syndrome in patients with connective tissue diseases.
keywords:

HELLP syndrome, antiphospholipid syndrome, systemic lupus erythematosus







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