Juvenile Dermatomyositis Overlapping with Madelung Disease

Gabriela Rybka; Mariusz Korkosz; Beata Machalica; Joanna Kosałka-Węgiel

doi:10.5114/dr.2024.150153

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Bieżący numer Archiwum Artykuły zaakceptowane O czasopiśmie Zeszyty specjalne Rada naukowa Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Standardy etyczne i procedury

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Otwarty dostęp

6/2024
vol. 111

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Opis przypadku

Juvenile Dermatomyositis Overlapping with Madelung Disease

Gabriela Rybka

¹

,

Mariusz Korkosz

^{1, 2}

,

Beata Machalica

³

,

Joanna Kosałka-Węgiel

^{1, 2}

Department of Rheumatology, Immunology and Internal Medicine, University Hospital, Krakow, Poland
Department of Rheumatology and Immunology, Jagiellonian University Medical College, Krakow, Poland
2nd Department of Internal Medicine, University Hospital, Krakow, Poland

Dermatol Rev/Przegl Dermatol 2024, 111, 456-460

DOI: https://doi.org/10.5114/dr.2024.150153

Data publikacji online: 2025/05/21

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Metryki PlumX:

Introduction:
Dermatomyositis belongs to the heterogeneous group of autoimmune inflammatory myopathies, whereas Madelung disease is a rare metabolic disorder characterized by symmetrical, non-encapsulated adipose tissue deposits.

Objective:
To the best of our knowledge, we present the first case in the literature with the coincidence of these two diseases.

Case report:
The patient was diagnosed with juvenile dermatomyositis at the age of 7 and was treated with steroids, azathioprine, and intravenous immunoglobulins. The diagnosis of Madelung disease was based on the physical examination and computed tomography scans when she was 42 years old. The patient declined surgical treatment for Madelung disease, and fibrate therapy did not provide any relief from her symptoms associated with the disease.

Conclusions:
We present the case of the coexistence of juvenile dermatomyositis, requiring long-term steroid therapy, with Madelung disease. Further research is needed to assess whether a diagnosis of juvenile dermatomyositis may increase the risk of developing Madelung disease.

Indeks osobowy

Juvenile Dermatomyositis Overlapping with Madelung Disease

Gabriela Rybka 1 , Mariusz Korkosz 1, 2 , Beata Machalica 3 , Joanna Kosałka-Węgiel 1, 2

Gabriela Rybka

¹

,

Mariusz Korkosz

^{1, 2}

,

Beata Machalica

³

,

Joanna Kosałka-Węgiel

^{1, 2}